Score E
Sequences producing significant alignments: (bits) Value
gi|6635203|dbj|BAA25486.2| (AB011132) KIAA0560 protein [Hom... 2731 0.0
gi|14750549|ref|XP_029045.1| KIAA0560 gene product [Homo sa... 2731 0.0
gi|7513019|pir||T00333 hypothetical protein KIAA0560 - human 2718 0.0
gi|7299528|gb|AAF54715.1| (AE003693) CG14730 gene product [... 1471 0.0
gi|3785995|gb|AAC67341.1| (AC005499) unknown protein [Arabi... 1252 0.0
gi|1899232|gb|AAB50008.1| (U90333) aquarius [Mus musculus] 846 0.0
gi|6425534|emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 com... 720 0.0
gi|12855010|dbj|BAB30194.1| (AK016322) putative [Mus musculus] 321 e-105
gi|7491705|pir||T40578 hypothetical protein SPBC646.02 - fi... 290 1e-76
gi|12861062|dbj|BAB32111.1| (AK020468) putative [Mus musculus] 167 7e-62
gi|7299526|gb|AAF54713.1| (AE003693) CG14729 gene product [... 219 6e-58
gi|14750542|ref|XP_029044.1| KIAA0560 gene product [Homo sa... 207 1e-51
gi|7243189|dbj|BAA92642.1| (AB037825) KIAA1404 protein [Hom... 121 8e-26
gi|14786300|ref|XP_030493.1| KIAA1404 protein [Homo sapiens] 121 8e-26
gi|10435893|dbj|BAB14696.1| (AK023836) unnamed protein prod... 121 8e-26
gi|14786304|ref|XP_030494.1| KIAA1404 protein [Homo sapiens... 121 8e-26
gi|9759443|dbj|BAB10240.1| (AB013394) prematurely terminate... 104 8e-21
gi|7493527|pir||T40065 tRNA-splicing endonuclease positive ... 103 2e-20
gi|6323726|ref|NP_013797.1| putative helicase; Nam7p [Sacch... 100 1e-19
gi|7490670|pir||T41111 hypothetical ATP binding protein - f... 100 3e-19
gi|11993646|gb|AAG42830.1|AF322655_1 (AF322655) regulator o... 94 1e-17
gi|13507601|ref|NP_109605.1| regulator of nonsense transcri... 94 1e-17
gi|13651985|ref|XP_018520.1| regulator of nonsense transcri... 94 1e-17
gi|4506479|ref|NP_002902.1| regulator of nonsense transcrip... 94 1e-17
gi|1885356|gb|AAC51140.1| (U59323) type 1 RNA helicase pNOR... 94 1e-17
gi|2739355|gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens] ... 94 1e-17
gi|1944407|dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens] 94 1e-17
gi|14766977|ref|XP_051416.1| regulator of nonsense transcri... 94 1e-17
gi|2498043|sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PR... 94 1e-17
gi|172574|gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerev... 93 2e-17
gi|6323462|ref|NP_013534.1| component of a nuclear-localize... 93 2e-17
gi|11595520|emb|CAC18314.1| (AL451022) probable HUPF1 prote... 93 3e-17
gi|6322835|ref|NP_012908.1| DNA helicase A; Hcs1p [Saccharo... 93 3e-17
gi|7488326|pir||T00533 SEN1 protein homolog T20K24.14 - Ara... 92 5e-17
gi|2340994|gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cer... 91 1e-16
gi|1175495|sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTE... 90 2e-16
gi|7510904|pir||T27684 hypothetical protein ZK1067.2 - Caen... 90 2e-16
gi|7492892|pir||T37779 probable regulator of nonsense trans... 90 2e-16
gi|7486511|pir||T08986 hypothetical protein F6G3.130 - Arab... 90 3e-16
gi|9954728|gb|AAG09081.1|AC026237_2 (AC026237) Similar to t... 87 1e-15
gi|2842700|sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTE... 87 2e-15
gi|7301121|gb|AAF56255.1| (AE003746) CG6204 gene product [D... 86 5e-15
gi|11359794|pir||T43280 nonsense-mediated mRNA decay trans-... 83 3e-14
gi|14738454|ref|XP_027828.1| KIAA0625 protein [Homo sapiens] 83 3e-14
gi|3327064|dbj|BAA31600.1| (AB014525) KIAA0625 protein [Hom... 83 3e-14
gi|7662212|ref|NP_055861.1| KIAA0625 protein [Homo sapiens]... 83 3e-14
gi|6321958|ref|NP_012034.1| DNA replication helicase; Dna2p... 82 5e-14
gi|2506893|sp|P51530|DN2L_HUMAN DNA2-LIKE HOMOLOG (DNA REPL... 81 9e-14
gi|14748403|ref|XP_052298.1| DNA2 (DNA replication helicase... 81 9e-14
gi|7446667|pir||G72429 hypothetical protein TM0005 - Thermo... 80 2e-13
gi|7446665|pir||D69085 transcription control factor enhance... 80 2e-13
gi|13904994|gb|AAH06779.1|AAH06779 (BC006779) Unknown (prot... 80 2e-13
gi|13812387|ref|NP_113505.1| component of a tRNA splicing c... 79 4e-13
gi|14738446|ref|XP_027829.1| KIAA0625 protein [Homo sapiens] 79 4e-13
gi|10303299|emb|CAC10094.1| (AL442164) related to SEN1 prot... 79 4e-13
gi|13559697|gb|AAK29903.1| (AC025721) Hypothetical protein ... 79 4e-13
gi|7446669|pir||T02699 hypothetical protein T18E12.6 - Arab... 77 2e-12
gi|11191231|emb|CAC16347.1| (AJ300306) putative helicase [A... 77 2e-12
gi|15027927|gb|AAK76494.1| (AY045820) putative helicase [Ar... 77 2e-12
gi|11498984|ref|NP_070217.1| DNA helicase, putative [Archae... 74 2e-11
gi|10177997|dbj|BAB11370.1| (AB017068) contains similarity ... 72 6e-11
gi|14521437|ref|NP_126913.1| DNA helicase, putative [Pyroco... 70 2e-10
gi|7514764|pir||D70476 DNA helicase - Aquifex aeolicus >gi|... 70 2e-10
gi|10177999|dbj|BAB11372.1| (AB017068) contains similarity ... 70 3e-10
gi|9758526|dbj|BAB08973.1| (AB024026) gb|AAD48967.1~gene_id... 70 3e-10
gi|10177744|dbj|BAB11057.1| (AB015478) contains similarity ... 70 3e-10
gi|7492541|pir||T41580 probable dna-binding protein - fissi... 69 4e-10
gi|6321024|ref|NP_011103.1| DNA Helicase I; Ecm32p [Sacchar... 69 5e-10
gi|13161880|emb|CAC33025.1| (AJ301641) hypothetical protein... 67 1e-09
gi|14590762|ref|NP_142832.1| DNA-binding protein [Pyrococcu... 66 4e-09
gi|6678029|ref|NP_033238.1| immunoglobulin S mu binding pro... 64 2e-08
gi|7465203|pir||D64588 probable DNA helicase - Helicobacter... 63 3e-08
gi|2498040|sp|Q60560|SMB2_MESAU DNA-BINDING PROTEIN SMUBP-2... 62 4e-08
gi|7490709|pir||T39568 hypothetical helicase - fission yeas... 62 6e-08
gi|11359050|pir||T51292 Dna2p - fission yeast (Schizosaccha... 62 6e-08
gi|908917|gb|AAA70430.1| (L24544) DNA helicase [Homo sapiens] 62 8e-08
gi|14766571|ref|XP_040834.1| immunoglobulin mu binding prot... 62 8e-08
gi|4504623|ref|NP_002171.1| immunoglobulin mu binding prote... 62 8e-08
gi|1082534|pir||A47500 Ig mu chain switch region binding pr... 62 8e-08
gi|6686403|gb|AAF23837.1|AC007234_9 (AC007234) F1E22.14 [Ar... 62 8e-08
gi|13928794|ref|NP_113774.1| immunoglobulin S mu binding pr... 60 2e-07
gi|14133261|dbj|BAB21860.2| (AB051556) KIAA1769 protein [Ho... 59 4e-07
gi|6686402|gb|AAF23836.1|AC007234_8 (AC007234) F1E22.16 [Ar... 59 4e-07
gi|14769950|ref|XP_028918.1| 34298 [Homo sapiens] 59 4e-07
gi|7485995|pir||T00740 hypothetical protein F22O13.35 - Ara... 59 5e-07
gi|14723930|ref|XP_038381.1| similar to regulator of nonsen... 59 5e-07
gi|10178000|dbj|BAB11373.1| (AB017068) contains similarity ... 59 6e-07
gi|5732068|gb|AAD48967.1|AF147263_9 (AF147263) contains sim... 59 6e-07
gi|7509302|pir||T26415 hypothetical protein Y106G6D.5 - Cae... 58 1e-06
gi|9758800|dbj|BAB09253.1| (AB026643) DNA helicase-like [Ar... 57 1e-06
gi|7295157|gb|AAF50482.1| (AE003556) CG7504 gene product [D... 56 4e-06
gi|10580995|gb|AAG19799.1| (AE005064) DNA helicase; Hel [Ha... 55 9e-06
gi|7291108|gb|AAF46543.1| (AE003449) CG2990 gene product [D... 52 5e-05
gi|8843991|gb|AAF80211.1|AF282853_19 (AF282853) Cag-omega [... 52 6e-05
gi|7497278|pir||T28788 hypothetical protein C41D11.7 - Caen... 51 1e-04
gi|7503321|pir||T22138 hypothetical protein F43G6.1b - Caen... 50 3e-04
gi|7503320|pir||T22132 hypothetical protein F43G6.1a - Caen... 50 3e-04
gi|183250|gb|AAA58611.1| (M64979) glial factor-1 [Homo sapi... 48 9e-04
gi|7302834|gb|AAF57908.1| (AE003804) CG6967 gene product [D... 48 0.001
gi|14572619|emb|CAC15528.3| (AL121829) dJ697K14.6 (Novel pr... 47 0.001
Alignments
>gi|6635203|dbj|BAA25486.2| (AB011132) KIAA0560 protein [Homo sapiens]
Length = 1556
Score = 2731 bits (7079), Expect(2) = 0.0
Identities = 1360/1428 (95%), Positives = 1360/1428 (95%)
Frame = +2
Query: 386 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXX 565
RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEI
Sbjct: 129 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPD 188
Query: 566 XXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 745
ILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG
Sbjct: 189 HFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 248
Query: 746 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 925
LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP
Sbjct: 249 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 308
Query: 926 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL 1105
LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL
Sbjct: 309 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL 368
Query: 1106 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA 1285
FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA
Sbjct: 369 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA 428
Query: 1286 EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 1465
EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ
Sbjct: 429 EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 488
Query: 1466 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 1645
IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES
Sbjct: 489 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 548
Query: 1646 TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA 1825
TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA
Sbjct: 549 TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA 608
Query: 1826 DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI 2005
DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI
Sbjct: 609 DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI 668
Query: 2006 QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM 2185
QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM
Sbjct: 669 QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM 728
Query: 2186 RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT 2365
RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT
Sbjct: 729 RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT 788
Query: 2366 FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRXXXXXXXXXXXXXXXL 2545
FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKR L
Sbjct: 789 FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTL 848
Query: 2546 IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII 2725
IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII
Sbjct: 849 IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII 908
Query: 2726 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGR 2905
SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDID TEKDFSRYGR
Sbjct: 909 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGR 968
Query: 2906 VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST 3085
VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST
Sbjct: 969 VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST 1028
Query: 3086 LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL 3265
LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL
Sbjct: 1029 LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL 1088
Query: 3266 RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL 3445
RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL
Sbjct: 1089 RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL 1148
Query: 3446 LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG 3625
LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG
Sbjct: 1149 LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG 1208
Query: 3626 RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF 3805
RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF
Sbjct: 1209 RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF 1268
Query: 3806 YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 3985
YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV
Sbjct: 1269 YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 1328
Query: 3986 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT 4165
TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT
Sbjct: 1329 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT 1388
Query: 4166 PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH 4345
PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH
Sbjct: 1389 PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH 1448
Query: 4346 HYHQTLLQLPPAMXXXXXXXXXXXXXXXXXXXXXXXXADIIPSPTDTSCRQETPAFQTDT 4525
HYHQTLLQLPPAM ADIIPSPTDTSCRQETPAFQTDT
Sbjct: 1449 HYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDT 1508
Query: 4526 TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 4669
TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
Sbjct: 1509 TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 1556
Score = 233 bits (593), Expect(2) = 0.0
Identities = 110/110 (100%), Positives = 110/110 (100%)
Frame = +1
Query: 61 FRFPRNAWAVVRVPYGTLKTEDIRPGAFVRRGVKRPGSNLREVDQGCRCPERSFSFHWSG 240
FRFPRNAWAVVRVPYGTLKTEDIRPGAFVRRGVKRPGSNLREVDQGCRCPERSFSFHWSG
Sbjct: 7 FRFPRNAWAVVRVPYGTLKTEDIRPGAFVRRGVKRPGSNLREVDQGCRCPERSFSFHWSG 66
Query: 241 GKSAAMAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 390
GKSAAMAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV
Sbjct: 67 GKSAAMAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 116
>gi|14750549|ref|XP_029045.1| KIAA0560 gene product [Homo sapiens]
Length = 1485
Score = 2731 bits (7079), Expect(2) = 0.0
Identities = 1360/1428 (95%), Positives = 1360/1428 (95%)
Frame = +2
Query: 386 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXX 565
RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEI
Sbjct: 58 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPD 117
Query: 566 XXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 745
ILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG
Sbjct: 118 HFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 177
Query: 746 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 925
LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP
Sbjct: 178 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 237
Query: 926 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL 1105
LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL
Sbjct: 238 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL 297
Query: 1106 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA 1285
FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA
Sbjct: 298 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA 357
Query: 1286 EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 1465
EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ
Sbjct: 358 EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 417
Query: 1466 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 1645
IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES
Sbjct: 418 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 477
Query: 1646 TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA 1825
TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA
Sbjct: 478 TYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRA 537
Query: 1826 DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI 2005
DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI
Sbjct: 538 DVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEI 597
Query: 2006 QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM 2185
QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM
Sbjct: 598 QGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIM 657
Query: 2186 RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT 2365
RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT
Sbjct: 658 RRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDT 717
Query: 2366 FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRXXXXXXXXXXXXXXXL 2545
FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKR L
Sbjct: 718 FLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTL 777
Query: 2546 IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII 2725
IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII
Sbjct: 778 IVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII 837
Query: 2726 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGR 2905
SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDID TEKDFSRYGR
Sbjct: 838 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGR 897
Query: 2906 VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST 3085
VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST
Sbjct: 898 VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST 957
Query: 3086 LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL 3265
LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL
Sbjct: 958 LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELL 1017
Query: 3266 RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL 3445
RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL
Sbjct: 1018 RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLL 1077
Query: 3446 LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG 3625
LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG
Sbjct: 1078 LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQG 1137
Query: 3626 RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF 3805
RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF
Sbjct: 1138 RARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYF 1197
Query: 3806 YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 3985
YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV
Sbjct: 1198 YQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 1257
Query: 3986 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT 4165
TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT
Sbjct: 1258 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELT 1317
Query: 4166 PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH 4345
PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH
Sbjct: 1318 PAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTH 1377
Query: 4346 HYHQTLLQLPPAMXXXXXXXXXXXXXXXXXXXXXXXXADIIPSPTDTSCRQETPAFQTDT 4525
HYHQTLLQLPPAM ADIIPSPTDTSCRQETPAFQTDT
Sbjct: 1378 HYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDT 1437
Query: 4526 TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 4669
TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
Sbjct: 1438 TPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 1485
Score = 95.5 bits (236), Expect(2) = 0.0
Identities = 45/45 (100%), Positives = 45/45 (100%)
Frame = +1
Query: 256 MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 390
MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV
Sbjct: 1 MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 45
>gi|7513019|pir||T00333 hypothetical protein KIAA0560 - human
Length = 1421
Score = 2718 bits (7046), Expect = 0.0
Identities = 1353/1421 (95%), Positives = 1353/1421 (95%)
Frame = +2
Query: 407 MLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXXXXXXXXX 586
MLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEI
Sbjct: 1 MLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFK 60
Query: 587 XILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLE 766
ILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLE
Sbjct: 61 HILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLE 120
Query: 767 LELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTM 946
LELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTM
Sbjct: 121 LELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTM 180
Query: 947 DKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDM 1126
DKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDM
Sbjct: 181 DKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDM 240
Query: 1127 LKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRES 1306
LKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRES
Sbjct: 241 LKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRES 300
Query: 1307 LVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQM 1486
LVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQM
Sbjct: 301 LVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQM 360
Query: 1487 PLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQD 1666
PLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQD
Sbjct: 361 PLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQD 420
Query: 1667 IEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLN 1846
IEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLN
Sbjct: 421 IEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLN 480
Query: 1847 VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDK 2026
VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDK
Sbjct: 481 VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDK 540
Query: 2027 GRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKEN 2206
GRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKEN
Sbjct: 541 GRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKEN 600
Query: 2207 NFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHL 2386
NFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHL
Sbjct: 601 NFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHL 660
Query: 2387 KASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRXXXXXXXXXXXXXXXLIVEPHVI 2566
KASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKR LIVEPHVI
Sbjct: 661 KASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVI 720
Query: 2567 PNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNF 2746
PNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNF
Sbjct: 721 PNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNF 780
Query: 2747 PEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNYVLAR 2926
PEQRTLIVTHSNQALNQLFEKIMALDID TEKDFSRYGRVNYVLAR
Sbjct: 781 PEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLAR 840
Query: 2927 RIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEV 3106
RIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEV
Sbjct: 841 RIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEV 900
Query: 3107 STFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRS 3286
STFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRS
Sbjct: 901 STFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRS 960
Query: 3287 KYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDG 3466
KYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDG
Sbjct: 961 KYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDG 1020
Query: 3467 FSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLC 3646
FSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLC
Sbjct: 1021 FSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLC 1080
Query: 3647 NLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEA 3826
NLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEA
Sbjct: 1081 NLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEA 1140
Query: 3827 EYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQ 4006
EYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQ
Sbjct: 1141 EYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQ 1200
Query: 4007 GQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLT 4186
GQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLT
Sbjct: 1201 GQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLT 1260
Query: 4187 ARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLL 4366
ARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLL
Sbjct: 1261 ARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLL 1320
Query: 4367 QLPPAMXXXXXXXXXXXXXXXXXXXXXXXXADIIPSPTDTSCRQETPAFQTDTTPSETGA 4546
QLPPAM ADIIPSPTDTSCRQETPAFQTDTTPSETGA
Sbjct: 1321 QLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDTTPSETGA 1380
Query: 4547 TSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 4669
TSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
Sbjct: 1381 TSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK 1421
>gi|7299528|gb|AAF54715.1| (AE003693) CG14730 gene product [Drosophila melanogaster]
Length = 1170
Score = 1471 bits (3808), Expect = 0.0
Identities = 733/1073 (68%), Positives = 870/1073 (80%), Gaps = 6/1073 (0%)
Frame = +2
Query: 1124 MLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRE 1303
MLKFYT FEIND TG++LT+++MT +HY +ITSLQRA FA FP L FALSNVA VD RE
Sbjct: 1 MLKFYTRFEINDVTGSSLTDHDMTQLHYKKITSLQRAVFAKFPSLRVFALSNVATVDNRE 60
Query: 1304 SLVKFFGPLSSNTLHQVASYLCLLP--TLPKNEDTTFDKEFLLELLVSRHERRISQIQQL 1477
SL + FG L L Q+A++L L+P + + D++FL ELL++RHERR SQ++ L
Sbjct: 61 SLEQHFGGLDGKGLLQIATFLNLVPEEVVSPLDWHRVDEQFLRELLITRHERRCSQLEAL 120
Query: 1478 NQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEI 1657
N+MPLYPTE+IIWDEN+VP+EYYSG+ CLALPKLNLQFLTLHDYLLRNFNLFRLESTYEI
Sbjct: 121 NEMPLYPTEQIIWDENVVPSEYYSGDSCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEI 180
Query: 1658 RQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTI 1837
RQDIED+VSRM PW+SE G VVFGGWARMA PI +F VVEVAKP++GE P+RVRADV +
Sbjct: 181 RQDIEDAVSRMLPWKSEDGDVVFGGWARMALPIASFAVVEVAKPHLGEKKPSRVRADVGV 240
Query: 1838 NLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGML 2017
L+VR IK EWE LRKHDVCFLITV+PT+PYGTK+ R PF+ QVGLV VRGCE++GML
Sbjct: 241 TLSVRREIKAEWENLRKHDVCFLITVKPTQPYGTKYKHREPFVPQVGLVSVRGCEVEGML 300
Query: 2018 DDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKP 2197
D GRVIEDGPEPRP L+GE+R +RV+LD NQY+ DM + +Q GA+DVYE+FNI+MRRKP
Sbjct: 301 DANGRVIEDGPEPRPQLQGENRCYRVWLDSNQYRLDMDD-LQEGADDVYESFNILMRRKP 359
Query: 2198 KENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSI 2377
KENNFKAVLETIR+LMNT+CVVP WLHDI+LGYGDP +AHYS MPNQ +L+FNDTF+
Sbjct: 360 KENNFKAVLETIRHLMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERSLEFNDTFMDY 419
Query: 2378 EHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRXXXXXXXXXXXXXXXLIVEP 2557
HL+ASFP +N+K V Q PPFR+ F + + ++V+P
Sbjct: 420 NHLEASFPQYNLKCEVPVENRQ-PPFRLIFEDVPIQKESDGEDPEEKPEEKLTKSILVQP 478
Query: 2558 HVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIY 2737
+ RGPYP ++PK+N+I+FT TQ+EAIRAGMQPGLT+VVGPPGTGKTDVAVQIISNIY
Sbjct: 479 YKYEARGPYPSDKPKQNSIRFTPTQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNIY 538
Query: 2738 HNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNYV 2917
HN P QRTLIVTHSNQALNQLFEKIMALDID TEKD+SRYGRVNYV
Sbjct: 539 HNHPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEALETEKDYSRYGRVNYV 598
Query: 2918 LARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVK-NKGSTLPD 3094
LA+R++LL +V++LQ++LGV GD +YTCETAGYF+LY VM+RWE++ S++ +KG +
Sbjct: 599 LAKRMDLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQISVHKGEADAE 658
Query: 3095 V--TEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLR 3268
E FPF ++FA+APQP+FKG +Y+E M+IA FR+I IF +LEEFRA ELLR
Sbjct: 659 KLRAEFEKEFPFGKFFADAPQPLFKGANYDELMDIACSNFRYISDIFNELEEFRAFELLR 718
Query: 3269 SGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLL 3448
+GLDRSKYLLVKEAKIIAMTCTHAALKR +LV LGF+YDNILMEE+AQILEIETFIPLLL
Sbjct: 719 TGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIETFIPLLL 778
Query: 3449 QNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGR 3628
QNP DG +RLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTR VR+GVPTVDLD QGR
Sbjct: 779 QNPLDGLNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLVRLGVPTVDLDGQGR 838
Query: 3629 ARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFY 3808
ARAS+C+LY WRYK L +L H+ E+ AN G ++D+QLINVEDF+GVGESEPNPYFY
Sbjct: 839 ARASICSLYKWRYKKLEDLQHIFERDEYKQANPGFVHDYQLINVEDFKGVGESEPNPYFY 898
Query: 3809 QNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVT 3988
QNL EAEY+VA++MYM LLGYPA KISILTTYNGQKHLIRD+IN RCGNNPLIG P+K+T
Sbjct: 899 QNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKHLIRDVINARCGNNPLIGWPHKIT 958
Query: 3989 TVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTP 4168
TVD++QGQQNDYIL+SLVRT+AVGHLRDVRRLVVAMSRARLGLY+F RVSLF+NC EL
Sbjct: 959 TVDKYQGQQNDYILISLVRTKAVGHLRDVRRLVVAMSRARLGLYVFGRVSLFKNCLELQQ 1018
Query: 4169 AFSQLTARPLHLHIIPTEPFPTTR-KNGERPSHEVQIIKNMPQMANFVYNMYM 4324
F LT RPL L ++P + FPT R + S +++ ++NM +MA FVY YM
Sbjct: 1019 TFKLLTQRPLKLSLVPEDKFPTDRLASAAVASQDIKTVENMSEMAQFVYERYM 1071
>gi|3785995|gb|AAC67341.1| (AC005499) unknown protein [Arabidopsis thaliana]
Length = 1444
Score = 1252 bits (3240), Expect = 0.0
Identities = 666/1342 (49%), Positives = 889/1342 (65%), Gaps = 37/1342 (2%)
Frame = +2
Query: 395 IRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXXXXX 574
++++M+LE SQYLENYLW N+ PE ++ ++MS+ M+NEKFRENV AW
Sbjct: 99 LQRVMILEVSQYLENYLWPNFDPETATFEHVMSMILMINEKFRENVAAWICFHDRDDLFK 158
Query: 575 XXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQL 754
+L+ + + ++ E+T L+F+ + F SLE ++ V L L W L
Sbjct: 159 KFLQKVLRL---KEGRDLTIAEKTNYLVFMINAFQSLEDAVVNEIVLSLAGLQSWHSLSY 215
Query: 755 ARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQ-------ERRFLSQLIQKFISVL 913
R ++EL P L K W K++ +K EA+ + + E F+ LI++F+ VL
Sbjct: 216 GRFQMELCLQPDLIKKW---KRSSKKWAAEAKSKGEKFDLSSSPEANFVRGLIEEFVEVL 272
Query: 914 K---------SVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCY 1066
S+ V V YCERF+E +ID+ LPTRR+ ++ D ++ C
Sbjct: 273 DHGVFADEVDDTAGSQLVDDSSVLYCERFMEFLIDMLNQLPTRRYLRPLVADIAVVAKCR 332
Query: 1067 LSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAH 1246
LS L + E+ G LF+QL+D+L+FY FEI D G LT++E HYDR + Q AF
Sbjct: 333 LSALYKHEK-GKLFAQLVDLLQFYEKFEIKDHDGTQLTDDEALQFHYDRFMAFQLLAFKK 391
Query: 1247 FPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFD-KEFL 1423
P+L D +L+N+ + L + LS L V +C L D D K+FL
Sbjct: 392 IPKLQDLSLANIGSIHKSSDLRRRLSVLSLEDLRDV---VCSKLKLVSRHDPWADSKDFL 448
Query: 1424 LELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLH 1603
E++VS E++ SQ + +N +PLYP E+I+WDE+++P+ YSGEGCLALPKLNLQFLTLH
Sbjct: 449 TEVVVSSFEKQQSQKEAINALPLYPNEQIMWDESVIPSINYSGEGCLALPKLNLQFLTLH 508
Query: 1604 DYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVA 1783
DYLLRNFNLFRLESTYEIR+DI+++V + + G F GW+RMA PI F + +V
Sbjct: 509 DYLLRNFNLFRLESTYEIREDIQEAVPHLLAHINNEGDTAFRGWSRMAVPINDFKIAQVK 568
Query: 1784 KPNIGENWPTRVRADVTINL-NVRDHIKDEWEGLRKHDVCFLITVRPT-KPYGTKFDRRR 1957
+PNIGE P+ V A+VT ++ + R I+ EW L++HDV FL+ +RP+ +P G + +
Sbjct: 569 QPNIGEEKPSSVTAEVTFSIKSYRTQIRSEWNSLKEHDVLFLLCIRPSFEPLGPEEADKA 628
Query: 1958 PFIEQVGLVYVRGCEIQGMLDDKGRVIED------GPEPRPNLRGESRTFRVFLDPNQYQ 2119
+++GL YVRGCEI + D++G ++ D E +P +GE RT V LD QY
Sbjct: 629 TVPQRLGLQYVRGCEIIDIRDEEGNLMNDFTGRVKRDEWKPP-KGEMRTVTVALDAAQYH 687
Query: 2120 QDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYG 2299
D+T+ + GAEDVY TFN++MRRKPKENNFKA+LE+IR+LMN C+VP+WLH++ LGYG
Sbjct: 688 IDVTDIAEKGAEDVYGTFNVLMRRKPKENNFKAILESIRDLMNEYCIVPEWLHNVFLGYG 747
Query: 2300 DPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQI---PPFRITFP 2470
+PS+A + MPN + +DF DTFL+ HL SF + V + A + PPFRIT P
Sbjct: 748 NPSAAQWPNMPNLLEIVDFKDTFLNANHLSESFSDYEVSFINAEGAEALDPSPPFRITLP 807
Query: 2471 -VRSGKG--------KKRXXXXXXXXXXXXXXXLIVEPHVIPNRGPYPYNQPKRNTIQFT 2623
G G + LIVE + P+ GPYP +QPK+N+++FT
Sbjct: 808 KTLKGNGAISGNKISEVNPADNVNMVDASPKEKLIVEAYTPPDPGPYPQDQPKQNSVKFT 867
Query: 2624 HTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLF 2803
TQ+ AI +G+QPGLTMVVGPPGTGKTD AVQI++ +YHN P QRTLI+THSNQALN LF
Sbjct: 868 PTQVGAIISGIQPGLTMVVGPPGTGKTDTAVQILNVLYHNCPSQRTLIITHSNQALNDLF 927
Query: 2804 EKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPG 2983
EKIM D+ T+ DFSR GRVN +L RR+ELL EV+RL +SL +P
Sbjct: 928 EKIMERDVPARYLLRLGQGEQELATDLDFSRQGRVNAMLVRRLELLSEVERLARSLQLPE 987
Query: 2984 DASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFK 3163
D YTCETAGYF+L V SRWE +++ V + FPF ++F++ P+P+F
Sbjct: 988 DVGYTCETAGYFWLLHVYSRWELFLAACAGNEDNQSFVRDR---FPFKDFFSDTPKPVFN 1044
Query: 3164 GRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAA 3343
G S+E+DM A+GCF H+K +F +LEE RA ELL+S DR+ YL+ K+AKI+AMTCTHAA
Sbjct: 1045 GESFEKDMRAAKGCFSHLKTVFQELEECRAFELLKSTADRANYLMTKQAKIVAMTCTHAA 1104
Query: 3344 LKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPV 3523
LKR D ++LGFKYDN+LMEE+AQILEIETFIP+LLQ +DG +RLKR I+IGDHHQLPPV
Sbjct: 1105 LKRRDFLQLGFKYDNLLMEESAQILEIETFIPMLLQRQEDGHARLKRCILIGDHHQLPPV 1164
Query: 3524 IKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLL 3703
+KNMAFQKYS+M+QSLFTRFVR+G+P ++L+AQGRAR SL LYNWRY++LG+L V+
Sbjct: 1165 VKNMAFQKYSHMDQSLFTRFVRLGIPYIELNAQGRARPSLAKLYNWRYRDLGDLSIVKEA 1224
Query: 3704 PEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADK 3883
P F ANAG Y++QL+NV D++G GES P+P+FYQN GEAEY+V++++YM LLGYPA+K
Sbjct: 1225 PIFQRANAGFSYEYQLVNVPDYEGRGESTPSPWFYQNQGEAEYIVSVYIYMRLLGYPANK 1284
Query: 3884 ISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGH 4063
ISILTTYNGQK LIRD+INRRC P IG P+KVTTVD+FQGQQND+ILLSLVRTR VGH
Sbjct: 1285 ISILTTYNGQKLLIRDVINRRCVPYPFIGPPSKVTTVDKFQGQQNDFILLSLVRTRFVGH 1344
Query: 4064 LRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRK 4243
LRDVRRLVVAMSRARLGLY+F R SLF+ C+EL P F L RP L + E T +
Sbjct: 1345 LRDVRRLVVAMSRARLGLYVFCRRSLFEQCYELQPTFQLLLQRPDRLGLNFNENTAYTDR 1404
Query: 4244 NGERPSHEVQIIKNMPQMANFV 4309
E + ++ ++ +MA+ V
Sbjct: 1405 VVEEVENS-YLVHDVEEMAHIV 1425
>gi|1899232|gb|AAB50008.1| (U90333) aquarius [Mus musculus]
Length = 552
Score = 846 bits (2185), Expect(3) = 0.0
Identities = 422/446 (94%), Positives = 427/446 (95%)
Frame = +2
Query: 386 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXX 565
RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWE
Sbjct: 65 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWETFKKKPD 124
Query: 566 XXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 745
ILKAALAETDGEFSLHEQT+LLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG
Sbjct: 125 HFPFFFKCILKAALAETDGEFSLHEQTLLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 184
Query: 746 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 925
LQ ARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLS+LIQKFISVLKS+P
Sbjct: 185 LQPARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSRLIQKFISVLKSIP 244
Query: 926 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHL 1105
LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLS+LV REEDGHL
Sbjct: 245 LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSSLVHREEDGHL 304
Query: 1106 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVA 1285
FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHF ELYDFALSNVA
Sbjct: 305 FSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFSELYDFALSNVA 364
Query: 1286 EVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 1465
EVD R+SLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ
Sbjct: 365 EVDARDSLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQ 424
Query: 1466 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 1645
IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES
Sbjct: 425 IQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLES 484
Query: 1646 TYEIRQDIEDSVSRMKPWQSEYGGVV 1723
TYEIRQDIEDSVSRMKPWQSEYGGVV
Sbjct: 485 TYEIRQDIEDSVSRMKPWQSEYGGVV 510
Score = 91.7 bits (226), Expect(3) = 0.0
Identities = 43/47 (91%), Positives = 44/47 (93%)
Frame = +1
Query: 250 AAMAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 390
AA P+QPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV
Sbjct: 6 AAQEPPSQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 52
Score = 34.7 bits (78), Expect(3) = 0.0
Identities = 15/29 (51%), Positives = 15/29 (51%)
Frame = +1
Query: 1729 WLGANGPAHCGFHCR*SGQTQHR*KLANP 1815
WLG PAHCGFHC QT K P
Sbjct: 515 WLGHGCPAHCGFHCSRGCQTPTSVKTGQP 543
>gi|6425534|emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 comes from this gene~cDNA EST yk27d4.5
comes from this gene~cDNA EST yk42b2.5 comes from this
gene~cDNA EST yk49b5.5 comes from this gene~cDNA EST
yk147h7.5 comes from this gene~cDNA EST yk192e10.5 comes
from this gene~cDNA>
Length = 1212
Score = 720 bits (1859), Expect = 0.0
Identities = 376/669 (56%), Positives = 456/669 (67%), Gaps = 67/669 (10%)
Frame = +2
Query: 2579 PYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQR 2758
PY Y+ P++N ++FT +Q+EAI++GMQPGLTMVVGPPGTGKTDVAVQIISNIYHN+P QR
Sbjct: 420 PYSYD-PRKNQVKFTPSQVEAIKSGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNWPNQR 478
Query: 2759 TLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNYVLARRIEL 2938
TLIVTHSNQALNQLFEKI+ALD+D TEKDFSRYGRVNYVL R++L
Sbjct: 479 TLIVTHSNQALNQLFEKIIALDVDERHLLRMGHGEEALETEKDFSRYGRVNYVLKERLQL 538
Query: 2939 LEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFF 3118
L V++L K+L + GD +YTCE AGYFF + V WEE+++KV +KG +S F
Sbjct: 539 LNCVEKLAKALKIVGDVAYTCENAGYFFRFSVCRVWEEFLAKVTSKGCNKLAEGIISEIF 598
Query: 3119 PFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDR----- 3283
PF +F + P +F G + D+++A C+RHI++IF +L+EFRA ELLR+G DR
Sbjct: 599 PFTGFFKDIPD-LFSGNN-SADLKVAHSCWRHIEQIFEKLDEFRAFELLRNGRDRTEYLL 656
Query: 3284 ----------------------SKYL---------------------------LVKEAKI 3316
SKY LVKEAKI
Sbjct: 657 VRRNWRKNWEFYVISFFLLFRFSKYYFRCRYYINTNRRRTRSMLFLDLCSFLSLVKEAKI 716
Query: 3317 IAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMI 3496
IAMTCTHAAL+R++LVKLGF+YDNI+MEEAAQILE+ETFIPLLLQNPQDG +RLKRWIMI
Sbjct: 717 IAMTCTHAALRRNELVKLGFRYDNIVMEEAAQILEVETFIPLLLQNPQDGHNRLKRWIMI 776
Query: 3497 GDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNL 3676
GDHHQLPPV++N AFQKYSNMEQSLF R VR+ VP V LD QGRARA + LY WRY L
Sbjct: 777 GDHHQLPPVVQNQAFQKYSNMEQSLFARLVRLSVPNVQLDRQGRARAQIAELYQWRYNGL 836
Query: 3677 GNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYM 3856
GNLPHV LP+F ANAG + FQ I++ DF G GE++P+P+FYQNLGEAEY AL+ YM
Sbjct: 837 GNLPHVDGLPQFQNANAGFAFPFQFIDIPDFNGHGETQPSPHFYQNLGEAEYACALYTYM 896
Query: 3857 CLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLS 4036
+LGYPA+KISILTTYNGQ LIRD+ RRC NPLIG P KV+TVD++QGQQND+I+LS
Sbjct: 897 RILGYPAEKISILTTYNGQAQLIRDVFQRRCDTNPLIGMPAKVSTVDKYQGQQNDFIILS 956
Query: 4037 LVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIP 4216
LV+TR +GH+RDVRRLVVA+SRARLGLY+ R +F +C ELTPA P L I+P
Sbjct: 957 LVKTRNIGHIRDVRRLVVALSRARLGLYVLGRSKVFMDCLELTPAMRIFAKYPRKLVILP 1016
Query: 4217 TEPFPTTRKNGERPSH----EVQI---------IKNMPQMANFVYNMYMHLIQTTHHYHQ 4357
E PT RK ER E+Q+ KN P NF + + TH H+
Sbjct: 1017 FEAHPTIRKWNERSKDGEPMEIQVRRVQFDGKWTKNKPNSRNFDKKSILDTLHMTHFVHE 1076
Query: 4358 TLLQLPPAM 4384
+ PAM
Sbjct: 1077 FYMSNLPAM 1085
Score = 240 bits (612), Expect = 1e-61
Identities = 147/362 (40%), Positives = 208/362 (56%), Gaps = 25/362 (6%)
Frame = +2
Query: 368 NHLLI*RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRE-NVPAWE 544
N +L F RKIM+LEFSQYLE YLW NY PE +SKA+ MSI M+NEKFRE N+ +W
Sbjct: 51 NEMLKTSFNSRKIMMLEFSQYLEAYLWPNYVPEKASKAWNMSIVVMINEKFRERNLDSWN 110
Query: 545 IXXXXXXXXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLI 724
IL+ +L E + E LL FL + F S+E ++ + ++L+
Sbjct: 111 CFTKKSEHFPHFFKSILQLSLQEEG--LASSEHCALLTFLVNAFGSVETPIVHKETRKLV 168
Query: 725 SLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFI 904
S+ +W GL ++ E KK KL+K W ++ +KM A + ER +L LI+KF
Sbjct: 169 SIEIWAGLLDSQREDLFKKQKKLKKIWENVR---QKMTAAAADNNEFERTYLWNLIEKFK 225
Query: 905 SVLKSVPLSEPV---------TMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLV 1057
VL S+ +E +D + YCERFIEL+IDLE++L TRR+FN++L SH+L
Sbjct: 226 RVLNSLEPNEAQESEEGEVRDPIDSIKYCERFIELLIDLESILQTRRFFNSVLHSSHILT 285
Query: 1058 HCYLSNLVRREEDGHLFSQLLDMLKFYTGFEIND--------------QTGNALTENEMT 1195
HC LS+L+ + G LF QL+ +LKFY FEI+D TG LT E++
Sbjct: 286 HCLLSSLISTDA-GSLFFQLVQLLKFYARFEIDDLSVIFFPVKKLYPNLTGRQLTHKEVS 344
Query: 1196 TIHYDRITSLQRAAFAHFPE-LYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCL 1372
HY +T LQ+AAF F E + +F + NV+ VDTR +L K FG ++ +++ A YL L
Sbjct: 345 EQHYQSVTRLQKAAFRLFNETMKEFYVLNVSGVDTRRALQKQFGDMNHAEVYRFAEYLHL 404
Query: 1373 LP 1378
+P
Sbjct: 405 VP 406
>gi|12855010|dbj|BAB30194.1| (AK016322) putative [Mus musculus]
Length = 310
Score = 321 bits (823), Expect(2) = e-105
Identities = 163/182 (89%), Positives = 166/182 (90%)
Frame = +2
Query: 386 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXX 565
RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWE
Sbjct: 115 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWETFKKKPD 174
Query: 566 XXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 745
ILKAALAETDGEFSLHEQT+LLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG
Sbjct: 175 HFPFFFKCILKAALAETDGEFSLHEQTLLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMG 234
Query: 746 LQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP 925
LQ ARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLS+LIQKFISVLKS+P
Sbjct: 235 LQPARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSRLIQKFISVLKSIP 294
Query: 926 LS 931
LS
Sbjct: 295 LS 296
Score = 84.7 bits (208), Expect(2) = e-105
Identities = 46/61 (75%), Positives = 46/61 (75%)
Frame = +1
Query: 208 PERSFSFHWSGGKSAAMAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIK 387
P SFS G S A PKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIK
Sbjct: 48 PLVSFSGDRCDGGSCA------PKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIK 101
Query: 388 V 390
V
Sbjct: 102 V 102
>gi|7491705|pir||T40578 hypothetical protein SPBC646.02 - fission yeast (Schizosaccharomyces
pombe)
gi|4160338|emb|CAA22806.1| (AL035216) hypothetical protein [Schizosaccharomyces pombe]
Length = 1284
Score = 290 bits (742), Expect = 1e-76
Identities = 306/1344 (22%), Positives = 568/1344 (41%), Gaps = 22/1344 (1%)
Frame = +2
Query: 374 LLI*RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXX 553
+++ + A + + LL + EN+LW + E+S ++ C ++ K + W++
Sbjct: 39 VIVSKDAKQVLSLLHELKLFENFLWQRVNTEMSLN-HINLTCMLLLYKSKYEYITWDLID 97
Query: 554 XXXXXXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLP 733
+ + E +L E ++ F+ CF ++ +R V QL ++
Sbjct: 98 ENRFQ-------LFFEKVIEVSLSLNLSEVVYMIQFITLCFQFSNIEKLRKLVYQLTNIS 150
Query: 734 MWMGLQ-LARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFIS- 907
+ L L +++ L + L K ++ K+ + + E+ L L+ ++I
Sbjct: 151 ILNSLDNLDKVKYLLHDSSSLTKAFDSYKE---------KRPSIVEKFPLHNLLSRWIHS 201
Query: 908 -VLKSVPLSEPVTMD-KVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLV 1081
++KS+ ++ + KV I + + L + PTRR+ + +++DS +S
Sbjct: 202 LLIKSISYAQTEKQEAKVTPLLAIINMSLVLLSAFPTRRFAHPVIEDSCFYTALRMSLYY 261
Query: 1082 RREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRIT--SLQRAAFAHFP- 1252
E LF ++ D L + F ++ GN + + I D + LQ F+ F
Sbjct: 262 DSNE---LFKKMTDDLNYVLKFPFDNTRGNEYEKEQK--IRNDELVYYHLQLTLFSDFQK 316
Query: 1253 ELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLEL 1432
EL D + R+ L + LS N+L + S L + P+ D EFL +
Sbjct: 317 ELGDLVFCTQTSLQQRQKLEEITSFLSFNSLKSLCSKCYLRTSFPEKYAIKVDFEFLKNV 376
Query: 1433 LVSRHERR--ISQIQQLNQMPLYPT--EKIIWDENIVPTEYYSGEGCLALPKLNLQFLTL 1600
++ ++R ++ ++ L E+ + D+ T Y+ L +Q+L++
Sbjct: 377 FINTYDRTRLVNDYDEIINFTLKDVLGERSVMDQENSLTNYF------LLQNTAIQYLSI 430
Query: 1601 HDYLLRNFNLFR---LESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTV 1771
++ + ++ L S Y + + R+ + ++ + F V
Sbjct: 431 SFFMRQQSKAYKKLLLRSLYAELLNFSEQYRRLSIKNATKNLTKDNFFS-----LNNFKV 485
Query: 1772 VEVAKPNIGENWPTRVRADVTINLNVRDH--IKDEWEGLRKHDVCFLITVRPTKPYGTKF 1945
VA P IG+ P V+ + ++ H ++D ++ +C + + +
Sbjct: 486 TSVAPPQIGQVLPQFVKCQMGLSRPGPFHSALRDLKNSIKSPFLCLIYISKDMEYKLLHG 545
Query: 1946 DRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQD 2125
+ P C DD G D N ++ V+L P Y
Sbjct: 546 NALDPLEGVTDFTIATICN-----DDVGMFQSDMQSDSDN-----KSINVYLSPFYYHS- 594
Query: 2126 MTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDP 2305
+ + + + FN + P+ N + L + +L+N P W D+ LG+G P
Sbjct: 595 LAGLGEYRPKQL--KFNFALVLSPEANKYWLDLNILVSLLNRAKEFPKWFEDLFLGFGTP 652
Query: 2306 SSAHYSKMPNQ-IATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSG 2482
+ PN + ++ + F ++E L++ P +V + +L I + +
Sbjct: 653 DICAF---PNAGLNSIYARNLFNTVEQLQSVLPNCHVPSNLSTESLLIKFY-------TN 702
Query: 2483 KGKKRXXXXXXXXXXXXXXXLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQP 2662
+ K ++P+ Y YN Q+E+I G QP
Sbjct: 703 QNKISADVTASDRHF-----------LLPSNRLYTYNDK----------QLESILRGSQP 741
Query: 2663 GLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXX 2842
GLTMV GP GK + +++ + P RT++++ SN ++N LF L+
Sbjct: 742 GLTMVNGPTRCGKHVLVCKLLEVLQDTSPNDRTVVLSDSNFSMNTLFT---LLEKARCFH 798
Query: 2843 XXXXXXXXXXXTEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFF 3022
++ RYG ++ +++ LL E+ RL S+ PG + +TA YF
Sbjct: 799 QGHLLYLSDEGKDETLERYGTLSSWISKLPGLLREIGRLAASIQAPGSHDASPDTALYFR 858
Query: 3023 LYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEG 3202
+ WE+Y++ V +K D + FPFH YF + + + + + + A
Sbjct: 859 DAYIKRLWEKYLNTVDDK-----DSVDAYNRFPFHSYFGDKSKRPIETYNKDNFFDYATK 913
Query: 3203 CFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKY 3382
+ ++ +F QLEE R LLR D+ Y L ++++II T T + + L + GF +
Sbjct: 914 LYGELEYMFQQLEEIRPFGLLRYYEDQELYALCQQSRIIGCTWTSLSTRLGTLKEKGFCF 973
Query: 3383 DNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNME 3562
+N+++ + I E LL GF RL +++G+ + N SN
Sbjct: 974 NNLIVMNSQNISESSITSILLSNCEPTGFDRL---VLLGNQYLTSG---NQDINNTSN-- 1025
Query: 3563 QSLFTRFVRVGVPTVDLDAQGRAR---ASLCN-LYNWRYKNLGNLPHVQLLPEFSTANAG 3730
SLF R + +DL+ Q R +SLC+ +Y K + + P+ +L N+G
Sbjct: 1026 GSLFKRLRYLKSRIIDLNTQYNVRESISSLCSSIYPLDIKTVDSSPNKRL----DYGNSG 1081
Query: 3731 LLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNG 3910
++ Q INV F+G E+EP + QNLGEAEY VALF YM +LGYP ++I I T Y
Sbjct: 1082 FAHEVQFINVGAFKGSQETEPVSGYKQNLGEAEYAVALFQYMRMLGYPTNEIVICTLYES 1141
Query: 3911 QKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQN-DYILLSLVRTRAVGHLRDVRRLV 4087
Q L+ +II+ RC +N G+P V TV++ + ++++ + V ++ + +
Sbjct: 1142 QVSLLNEIISVRCSHNSFFGQPAFVGTVEKLPSDKRVNFVIFTTVESKEASDHWNPKTFY 1201
Query: 4088 VAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHE 4267
A S GLY+ LF++ L ++++ P L + E +P++ K G S E
Sbjct: 1202 KAFSACSYGLYVLCNRDLFRSTRGLEKLWNEIEKTPDKLLLTTGEIYPSSHKIGS--SVE 1259
Query: 4268 VQIIKNMPQMANFVYNMYMHLIQT 4339
I+N+ ++N+V M + T
Sbjct: 1260 TFEIENLLHLSNYVVEMTKKRLNT 1283
>gi|12861062|dbj|BAB32111.1| (AK020468) putative [Mus musculus]
Length = 197
Score = 167 bits (423), Expect(2) = 7e-62
Identities = 83/102 (81%), Positives = 86/102 (83%)
Frame = +2
Query: 386 RFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXX 565
RFAIRKIMLLEFSQYL+NYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWE
Sbjct: 58 RFAIRKIMLLEFSQYLKNYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWETFKKKPD 117
Query: 566 XXXXXXXXILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEV 691
ILKAALAETDGEFSLHEQT+LLLFLDHCFNSL +
Sbjct: 118 HFPFFFKCILKAALAETDGEFSLHEQTLLLLFLDHCFNSLVI 159
Score = 95.5 bits (236), Expect(2) = 7e-62
Identities = 45/45 (100%), Positives = 45/45 (100%)
Frame = +1
Query: 256 MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 390
MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV
Sbjct: 1 MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKV 45
>gi|7299526|gb|AAF54713.1| (AE003693) CG14729 gene product [Drosophila melanogaster]
Length = 320
Score = 219 bits (558), Expect(2) = 6e-58
Identities = 114/243 (46%), Positives = 155/243 (62%), Gaps = 3/243 (1%)
Frame = +2
Query: 398 RKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIXXXXXXXXXX 577
R+I +LEFSQYLE YLW +Y E ++ A+LMSI M NEKFRE V W +
Sbjct: 77 RRINMLEFSQYLEQYLWPHYQRETATHAHLMSIVIMANEKFRERVEVWTVFEKLPDQYPA 136
Query: 578 XXXXILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGL 748
+L++ L + +L E+T LL+F++HCFNS+E++L R Q ++L+SL MW L
Sbjct: 137 FFRHVLESCLPSKKAKEASSTLRERTALLMFINHCFNSMEIELCREQAKRLVSLSMWHCL 196
Query: 749 QLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPL 928
Q R E EL++ P+ RK+W + K ++ PE ER F+ LI F+ +L+S+P
Sbjct: 197 QPRRREQELREVPEWRKYWKRLLKKEKDSKPEV----LWERHFMQNLIIDFLHILESIPA 252
Query: 929 SEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLF 1108
V + VHYCERF+E +IDLEALLPTRR+FNT+LDD HL+V LS LVRREE G LF
Sbjct: 253 EGEVPRNVVHYCERFLEFIIDLEALLPTRRFFNTVLDDCHLIVRALLSPLVRREE-GKLF 311
Query: 1109 SQL 1117
Q+
Sbjct: 312 GQV 314
Score = 30.4 bits (67), Expect(2) = 6e-58
Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Frame = +1
Query: 295 TVSQINAEFVTQLACKYWAPHIKKKS-PFDIKV 390
TVSQ++++ + QLA +YW P K P+ K+
Sbjct: 27 TVSQLSSDVIWQLASQYWTPDTKADHLPYSAKI 59
>gi|14750542|ref|XP_029044.1| KIAA0560 gene product [Homo sapiens]
Length = 128
Score = 207 bits (526), Expect = 1e-51
Identities = 104/128 (81%), Positives = 104/128 (81%)
Frame = +2
Query: 4286 MPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMXXXXXXXXXXXXXXXXXXXXXXXXADI 4465
MPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAM ADI
Sbjct: 1 MPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADI 60
Query: 4466 IPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDA 4645
IPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDA
Sbjct: 61 IPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDA 120
Query: 4646 TSAPEETK 4669
TSAPEETK
Sbjct: 121 TSAPEETK 128
>gi|7243189|dbj|BAA92642.1| (AB037825) KIAA1404 protein [Homo sapiens]
Length = 1925
Score = 121 bits (303), Expect = 8e-26
Identities = 99/313 (31%), Positives = 155/313 (48%), Gaps = 5/313 (1%)
Frame = +2
Query: 3218 KKIFTQLEEFRASELLRSGLDRSKYL-LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNIL 3394
+KI + ++R S + L + L ++K+A+++ MT T AA R L K+ + ++
Sbjct: 954 RKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRI--VI 1011
Query: 3395 MEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLF 3574
+EEAA++LE T L + I+IGDH QL P K N+E SLF
Sbjct: 1012 VEEAAEVLEAHTIATLS--------KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLF 1063
Query: 3575 TRFVRVGVPTVDLDAQGRARASLCNLYNWR-YKNLGNLPHVQLLPEFSTANAGLLYDFQL 3751
R V+V +P V L+ Q R + L Y++L N P V + ++ L +
Sbjct: 1064 ERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHN 1123
Query: 3752 INVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRD 3931
++ Q G+S +QN EA +VV L Y Y +I+ILTTY GQ +R
Sbjct: 1124 FPEQEIQ-EGKS------HQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRK 1176
Query: 3932 IINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSR 4102
++ + +V VD++QG++ND ILLSLVR+ VG L+ R+ VA+SR
Sbjct: 1177 LMPAKTFAGV------RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSR 1230
Query: 4103 ARLGLYIFARVSL 4141
A+ G+Y + +
Sbjct: 1231 AKKGMYCIGNMQM 1243
Score = 46.6 bits (109), Expect = 0.003
Identities = 27/86 (31%), Positives = 45/86 (51%), Gaps = 10/86 (11%)
Frame = +2
Query: 2585 PYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHN------- 2743
P P + ++ +Q+EA++ + L ++ GPPGTGKT V ++I+ + N
Sbjct: 594 PGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQIS 653
Query: 2744 ---FPEQRTLIVTHSNQALNQLFEKI 2812
FP L+V ++N AL+Q E I
Sbjct: 654 LQKFP---ILVVCYTNHALDQFLEGI 676
>gi|14786300|ref|XP_030493.1| KIAA1404 protein [Homo sapiens]
Length = 1137
Score = 121 bits (303), Expect = 8e-26
Identities = 99/313 (31%), Positives = 155/313 (48%), Gaps = 5/313 (1%)
Frame = +2
Query: 3218 KKIFTQLEEFRASELLRSGLDRSKYL-LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNIL 3394
+KI + ++R S + L + L ++K+A+++ MT T AA R L K+ + ++
Sbjct: 239 RKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRI--VI 296
Query: 3395 MEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLF 3574
+EEAA++LE T L + I+IGDH QL P K N+E SLF
Sbjct: 297 VEEAAEVLEAHTIATLS--------KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLF 348
Query: 3575 TRFVRVGVPTVDLDAQGRARASLCNLYNWR-YKNLGNLPHVQLLPEFSTANAGLLYDFQL 3751
R V+V +P V L+ Q R + L Y++L N P V + ++ L +
Sbjct: 349 ERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHN 408
Query: 3752 INVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRD 3931
++ Q G+S +QN EA +VV L Y Y +I+ILTTY GQ +R
Sbjct: 409 FPEQEIQ-EGKS------HQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRK 461
Query: 3932 IINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSR 4102
++ + +V VD++QG++ND ILLSLVR+ VG L+ R+ VA+SR
Sbjct: 462 LMPAKTFAGV------RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSR 515
Query: 4103 ARLGLYIFARVSL 4141
A+ G+Y + +
Sbjct: 516 AKKGMYCIGNMQM 528
>gi|10435893|dbj|BAB14696.1| (AK023836) unnamed protein product [Homo sapiens]
Length = 1137
Score = 121 bits (303), Expect = 8e-26
Identities = 99/313 (31%), Positives = 155/313 (48%), Gaps = 5/313 (1%)
Frame = +2
Query: 3218 KKIFTQLEEFRASELLRSGLDRSKYL-LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNIL 3394
+KI + ++R S + L + L ++K+A+++ MT T AA R L K+ + ++
Sbjct: 239 RKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRI--VI 296
Query: 3395 MEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLF 3574
+EEAA++LE T L + I+IGDH QL P K N+E SLF
Sbjct: 297 VEEAAEVLEAHTIATLS--------KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLF 348
Query: 3575 TRFVRVGVPTVDLDAQGRARASLCNLYNWR-YKNLGNLPHVQLLPEFSTANAGLLYDFQL 3751
R V+V +P V L+ Q R + L Y++L N P V + ++ L +
Sbjct: 349 ERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHN 408
Query: 3752 INVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRD 3931
++ Q G+S +QN EA +VV L Y Y +I+ILTTY GQ +R
Sbjct: 409 FPEQEIQ-EGKS------HQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRK 461
Query: 3932 IINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSR 4102
++ + +V VD++QG++ND ILLSLVR+ VG L+ R+ VA+SR
Sbjct: 462 LMPAKTFAGV------RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSR 515
Query: 4103 ARLGLYIFARVSL 4141
A+ G+Y + +
Sbjct: 516 AKKGMYCIGNMQM 528
>gi|14786304|ref|XP_030494.1| KIAA1404 protein [Homo sapiens]
gi|13274194|emb|CAC33877.1| (AL049766) dJ686N3.2.1 (KIAA1404 protein, isoform 1) [Homo sapiens]
Length = 1918
Score = 121 bits (303), Expect = 8e-26
Identities = 99/313 (31%), Positives = 155/313 (48%), Gaps = 5/313 (1%)
Frame = +2
Query: 3218 KKIFTQLEEFRASELLRSGLDRSKYL-LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNIL 3394
+KI + ++R S + L + L ++K+A+++ MT T AA R L K+ + ++
Sbjct: 947 RKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRI--VI 1004
Query: 3395 MEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLF 3574
+EEAA++LE T L + I+IGDH QL P K N+E SLF
Sbjct: 1005 VEEAAEVLEAHTIATLS--------KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLF 1056
Query: 3575 TRFVRVGVPTVDLDAQGRARASLCNLYNWR-YKNLGNLPHVQLLPEFSTANAGLLYDFQL 3751
R V+V +P V L+ Q R + L Y++L N P V + ++ L +
Sbjct: 1057 ERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHN 1116
Query: 3752 INVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRD 3931
++ Q G+S +QN EA +VV L Y Y +I+ILTTY GQ +R
Sbjct: 1117 FPEQEIQ-EGKS------HQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRK 1169
Query: 3932 IINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSR 4102
++ + +V VD++QG++ND ILLSLVR+ VG L+ R+ VA+SR
Sbjct: 1170 LMPAKTFAGV------RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSR 1223
Query: 4103 ARLGLYIFARVSL 4141
A+ G+Y + +
Sbjct: 1224 AKKGMYCIGNMQM 1236
Score = 46.6 bits (109), Expect = 0.003
Identities = 27/86 (31%), Positives = 45/86 (51%), Gaps = 10/86 (11%)
Frame = +2
Query: 2585 PYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHN------- 2743
P P + ++ +Q+EA++ + L ++ GPPGTGKT V ++I+ + N
Sbjct: 587 PGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQIS 646
Query: 2744 ---FPEQRTLIVTHSNQALNQLFEKI 2812
FP L+V ++N AL+Q E I
Sbjct: 647 LQKFP---ILVVCYTNHALDQFLEGI 669
>gi|9759443|dbj|BAB10240.1| (AB013394) prematurely terminated mRNA decay factor-like protein
[Arabidopsis thaliana]
Length = 1235
Score = 104 bits (260), Expect = 8e-21
Identities = 87/283 (30%), Positives = 137/283 (47%), Gaps = 7/283 (2%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
+ + A +I TC AA DL F++ +L++E+ Q E E IPL+L
Sbjct: 623 ITQSADVICCTCVGAA----DLRLSNFRFRQVLIDESTQATEPECLIPLVLG-------- 670
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
+K+ +++GDH QL PVI + + + QSLF R V +G+ + L Q R +L
Sbjct: 671 VKQVVLVGDHCQLGPVIMCKKAAR-AGLAQSLFERLVTLGIKPIRLQVQYRMHPALSEFP 729
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDF----QGVGESEPNPYFYQNLGE 3823
+ + G L + + E T G+ + + + N F G E + Y N E
Sbjct: 730 SNSFYE-GTLQNGVTIIERQTT--GIDFPWPVPNRPMFFYVQLGQEEISASGTSYLNRTE 786
Query: 3824 AEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRF 4003
A V L G +I ++T Y GQ+ I + + R + + +V +VD F
Sbjct: 787 AANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSF 846
Query: 4004 QGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
QG++ DYI+LS VR+ + +G L D RRL VA++RAR G+ I
Sbjct: 847 QGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVI 889
Score = 46.2 bits (108), Expect = 0.003
Identities = 29/92 (31%), Positives = 50/92 (53%), Gaps = 2/92 (2%)
Frame = +2
Query: 2549 VEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIIS 2728
VE ++ N P + P + +Q+ A+++ +Q ++++ GPPGTGKT + I
Sbjct: 465 VEAQMVRNTLPRRFGVP--GLPELNASQVNAVKSVLQKPISLIQGPPGTGKTVTSAAI-- 520
Query: 2729 NIYH--NFPEQRTLIVTHSNQALNQLFEKIMA 2818
+YH + + L+ SN A++QL EKI A
Sbjct: 521 -VYHMAKQGQGQVLVCAPSNVAVDQLAEKISA 551
>gi|7493527|pir||T40065 tRNA-splicing endonuclease positive effector - fission yeast
(Schizosaccharomyces pombe)
gi|4007798|emb|CAA22438.1| (AL034463) tRNA-splicing endonuclease positive effector
[Schizosaccharomyces pombe]
Length = 1944
Score = 103 bits (257), Expect = 2e-20
Identities = 133/539 (24%), Positives = 224/539 (40%), Gaps = 47/539 (8%)
Frame = +2
Query: 2648 AGMQPGLTMVVGPPGTGKTDVAVQIIS--------NIYHNFPEQ-------RTLIVTHSN 2782
+ + G T++ GPPGTGKT + +I + N P Q + LI SN
Sbjct: 1282 SSVNDGFTLIQGPPGTGKTKTILGMIGAVLTSSSQGLQFNVPGQTRKTSKNKILICAPSN 1341
Query: 2783 QALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNY-----VLARRIELLEE 2947
A++++ +I A D K F + RV + V A+ L E+
Sbjct: 1342 AAIDEILLRIKAGVYDHEGI-------------KFFPKVIRVGFGDSISVHAKEFTLEEQ 1388
Query: 2948 -VKRLQ-KSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFP 3121
+K+++ +L +A+ + +T ++Y S +K + S D+
Sbjct: 1389 MIKQMELTNLKKDQEANNSSDTR------------KKYDSIIKKRDSLREDLE------- 1429
Query: 3122 FHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEF------------RASELL 3265
K RS ++ I E R I K LE+ R ++L
Sbjct: 1430 -------------KFRSTGKNSSILEAQLREITKQKNMLEQSLDDMRERQRSTNRNLDVL 1476
Query: 3266 RSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLV-KLGFKYDNILMEEAAQILEIETFIPL 3442
+ + L++EA I+ C + H+L+ G + ++++EAAQ +E+ + IPL
Sbjct: 1477 KKQIQNQ---LLQEADIV---CATLSASGHELLLNAGLTFRTVIIDEAAQAVELSSIIPL 1530
Query: 3443 LLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTR-FVRVGVPTVDLDA 3619
+ +M+GD +QLPP + + K+ QSL+ R F + L
Sbjct: 1531 KYG--------CESCVMVGDPNQLPPTVLSKTSAKFG-YSQSLYVRMFKQHNESACLLSI 1581
Query: 3620 QGRARASLCNL-----YNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGE 3784
Q R + YN + + N+ V P G+ F + E F
Sbjct: 1582 QYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPWHEDPQLGIYRFFNVHGTEAFS---- 1637
Query: 3785 SEPNPYFYQNLGEAEYVVALF--MYMCLLGYPAD-KISILTTYNGQKHLIRDIINRRCGN 3955
N N+ EA +++ L+ + C L + KI ++T Y Q +R R+ G+
Sbjct: 1638 ---NSKSLYNVEEASFILLLYERLIQCYLNIDFEGKIGVVTPYRSQVQQLRSQFQRKYGS 1694
Query: 3956 NPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYI 4123
+I + + TVD FQGQ+ D I+ S VR+ +G L+D+RRL VA++RA+ LYI
Sbjct: 1695 --IIFKHLDIHTVDGFQGQEKDIIIFSCVRSSMSGGIGFLQDLRRLNVALTRAKSSLYI 1751
>gi|6323726|ref|NP_013797.1| putative helicase; Nam7p [Saccharomyces cerevisiae]
gi|400350|sp|P30771|NAM7_YEAST NAM7 PROTEIN (NONSENSE-MEDIATED MRNA DECAY PROTEIN 1) (UP-FRAMESHIFT
SUPPRESSOR 1)
gi|83347|pir||S23408 prematurely terminated mRNA decay factor NAM7 - yeast (Saccharomyces
cerevisiae)
gi|4023|emb|CAA44266.1| (X62394) helicase [Saccharomyces cerevisiae]
gi|173142|gb|AAA35197.1| (M76659) zinc finger protein [Saccharomyces cerevisiae]
gi|807962|emb|CAA89226.1| (Z49259) Nam7p [Saccharomyces cerevisiae]
Length = 971
Score = 100 bits (249), Expect = 1e-19
Identities = 88/318 (27%), Positives = 154/318 (47%), Gaps = 8/318 (2%)
Frame = +2
Query: 3194 AEGCFRHIKKIFTQLEEFRASELLR--SGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVK 3367
A+G +++ K+ ++ E AS+ R + +++ ++ +A ++ TC A KR D
Sbjct: 507 AKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLDT-- 564
Query: 3368 LGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQK 3547
K+ +L++E+ Q E E IP++ K+ I++GDH QL PVI
Sbjct: 565 ---KFRTVLIDESTQASEPECLIPIV--------KGAKQVILVGDHQQLGPVILERKAAD 613
Query: 3548 YSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNL-YNWRYKNLGNLPHVQLLPEFSTAN 3724
+ ++QSLF R + +G + L+ Q R L N Y+ G+L + + + + N
Sbjct: 614 -AGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYE--GSLQNGVTIEQRTVPN 670
Query: 3725 AGLLYDFQLINVEDFQGVGESE--PNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILT 3898
+ + + I + + G E N + N EA + + G ++I ++T
Sbjct: 671 SKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVIT 730
Query: 3899 TYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRT---RAVGHLR 4069
Y GQ+ I + + + +V +VD FQG++ DYI+LS VR +A+G LR
Sbjct: 731 PYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLR 790
Query: 4070 DVRRLVVAMSRARLGLYI 4123
D RRL V ++RA+ GL I
Sbjct: 791 DPRRLNVGLTRAKYGLVI 808
Score = 41.2 bits (95), Expect = 0.11
Identities = 25/83 (30%), Positives = 41/83 (49%)
Frame = +2
Query: 2579 PYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQR 2758
P P N Q +Q A+ +Q L+++ GPPGTGKT + I+ ++ + R
Sbjct: 396 PLPKEFSIPNFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHL-SKIHKDR 454
Query: 2759 TLIVTHSNQALNQLFEKIMALDI 2827
L+ SN A++ L K+ L +
Sbjct: 455 ILVCAPSNVAVDHLAAKLRDLGL 477
>gi|7490670|pir||T41111 hypothetical ATP binding protein - fission yeast
(Schizosaccharomyces pombe)
gi|3581879|emb|CAA20777.1| (AL031540) hypothetical protein [Schizosaccharomyces pombe]
Length = 1015
Score = 99.8 bits (247), Expect = 3e-19
Identities = 92/289 (31%), Positives = 133/289 (45%), Gaps = 6/289 (2%)
Frame = +2
Query: 3293 LLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFS 3472
+L++ A +I MT T R L ++ K +EEAA +LE IP + F
Sbjct: 678 ILLRGANVIGMTTTGLNKYRDILERINPKI--CFIEEAADVLE-GPIIPAV-------FP 727
Query: 3473 RLKRWIMIGDHHQLPPVIKNMAF-QKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCN 3649
L++ ++IGDH QL P A Q N+ S+F R V + L Q R +
Sbjct: 728 SLEQLVLIGDHKQLRPGCSTYALRQDPFNLSISMFERLVENDMEYTRLTMQRRMHPQIRR 787
Query: 3650 LYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLIN--VEDFQGVGESEPNPYFYQNLGE 3823
L + Y++L + + P S G + F L + +ED G NL E
Sbjct: 788 LVSSVYEDLSDYEITKYWP--SIPGMGEIRRFFLTHSRIEDNDGFASKI-------NLFE 838
Query: 3824 AEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRF 4003
A+ +V +Y+ G KI+ LT Y QK LI +++ KV TVD +
Sbjct: 839 AQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERLLSESLNREKHF---IKVATVDGY 895
Query: 4004 QGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYIFARVSL 4141
QG++ND +LLSLVR VG L R+ V++SRAR GL+IF L
Sbjct: 896 QGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRGLFIFGNAQL 944
Score = 35.8 bits (81), Expect = 4.5
Identities = 17/65 (26%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Frame = +2
Query: 2627 TQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQ--RTLIVTHSNQALNQL 2800
+Q++A ++ + L+++ GPPGTGK+ V ++ I + N L+ +N A++Q+
Sbjct: 375 SQLKAYQSMLTKRLSIIQGPPGTGKSFVTLKAIETLLENTHSHVLPILVACQTNHAVDQI 434
Query: 2801 FEKIM 2815
+++
Sbjct: 435 LIRLL 439
>gi|11993646|gb|AAG42830.1|AF322655_1 (AF322655) regulator of nonsense transcripts 1 [Mus musculus]
Length = 1113
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 601 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 648
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 649 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 707
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 708 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 760
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 761 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 820
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 821 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 867
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 455 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 511
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 512 VLVCAPSNIAVDQLTEKI 529
>gi|13507601|ref|NP_109605.1| regulator of nonsense transcripts 1; nonsense mRNA reducing factor 1
[Mus musculus]
gi|12836885|gb|AAK08652.1|AF182947_1 (AF182947) nonsense mRNA reducing factor 1 NORF1 [Mus musculus]
Length = 1113
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 601 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 648
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 649 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 707
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 708 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 760
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 761 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 820
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 821 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 867
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 455 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 511
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 512 VLVCAPSNIAVDQLTEKI 529
>gi|13651985|ref|XP_018520.1| regulator of nonsense transcripts 1 [Homo sapiens]
gi|14766973|ref|XP_051417.1| regulator of nonsense transcripts 1 [Homo sapiens]
gi|14766982|ref|XP_051418.1| regulator of nonsense transcripts 1 [Homo sapiens]
Length = 935
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 606 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 653
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 654 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 712
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 713 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 766 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 825
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 826 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 872
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 460 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 516
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 517 VLVCAPSNIAVDQLTEKI 534
>gi|4506479|ref|NP_002902.1| regulator of nonsense transcripts 1 [Homo sapiens]
gi|1575536|gb|AAC50771.1| (U65533) regulator of nonsense transcript stability [Homo sapiens]
Length = 1118
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 606 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 653
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 654 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 712
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 713 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 766 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 825
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 826 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 872
Score = 47.8 bits (112), Expect = 0.001
Identities = 30/78 (38%), Positives = 44/78 (55%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQR-- 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I +YH +
Sbjct: 460 PKRFTAQALPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATI---VYHLARQDNGP 516
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 517 VLVCAPSNIAVDQLTEKI 534
>gi|1885356|gb|AAC51140.1| (U59323) type 1 RNA helicase pNORF1 [Homo sapiens]
Length = 1118
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 606 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 653
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 654 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 712
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 713 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 766 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 825
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 826 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 872
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 460 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 516
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 517 VLVCAPSNIAVDQLTEKI 534
>gi|2739355|gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens]
gi|3328175|gb|AAC26788.1| (AF074016) nonsense-mediated mRNA decay trans-acting factor [Homo
sapiens]
Length = 1118
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 606 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 653
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 654 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 712
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 713 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 766 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 825
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 826 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 872
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 460 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 516
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 517 VLVCAPSNIAVDQLTEKI 534
>gi|1944407|dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens]
Length = 1129
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 617 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 664
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 665 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 723
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 724 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 776
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 777 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 836
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 837 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 883
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 471 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 527
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 528 VLVCAPSNIAVDQLTEKI 545
>gi|14766977|ref|XP_051416.1| regulator of nonsense transcripts 1 [Homo sapiens]
Length = 946
Score = 94.4 bits (233), Expect = 1e-17
Identities = 86/287 (29%), Positives = 136/287 (46%), Gaps = 11/287 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC A R L K+ F+ +IL++E+ Q E E +P++L
Sbjct: 617 LLMNADVICCTCVGAGDPR--LAKMQFR--SILIDESTQATEPECMVPVVLG-------- 664
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ I++GDH QL PV+ K + + QSLF R V +G+ + L Q R +L
Sbjct: 665 AKQLILVGDHCQLGPVVMCKKAAK-AGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFP 723
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLL--YDFQLINVED------FQGVGESEPNPYFYQ 3811
+ N+ + L TA + +DFQ + QG E + Y
Sbjct: 724 S-------NIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 776
Query: 3812 NLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
N EA V + + G D+I I+T Y GQ+ + + + + + ++ +
Sbjct: 777 NRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 836
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
VD FQG++ D+I+LS VR + +G L D RRL VA++RAR G+ I
Sbjct: 837 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 883
Score = 47.4 bits (111), Expect = 0.001
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2597 PKRNTIQ----FTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYH--NFPEQR 2758
PKR T Q H+Q+ A++ +Q L+++ GPPGTGKT + I+ ++ N P
Sbjct: 471 PKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGP--- 527
Query: 2759 TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 528 VLVCAPSNIAVDQLTEKI 545
>gi|2498043|sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PROTEIN MJ0104
gi|2129217|pir||H64312 probable DNA helicase MJ0104 - Methanococcus jannaschii
gi|1590880|gb|AAB98084.1| (U67467) DNA-binding protein, probably DNA helicase [Methanococcus
jannaschii]
Length = 663
Score = 94.0 bits (232), Expect = 1e-17
Identities = 120/522 (22%), Positives = 220/522 (41%), Gaps = 21/522 (4%)
Frame = +2
Query: 2645 RAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALD 2824
+A + L ++ GPPGTGKT ++I F + + L SN A + + E ++
Sbjct: 195 KAVLSRDLYLIHGPPGTGKTRTITEVIVQEV-KFNKHKVLATADSNIAADNILEYLIKKY 253
Query: 2825 IDXXXXXXXXXXXXXXXTEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCE 3004
D KD ++ + Y L+E ++ Q+ L + E
Sbjct: 254 PDLKVVRVGHPTRIS----KDLIQHS-LPY-------LIENHEKYQEILALREKIKEIKE 301
Query: 3005 TAGYFFLYQVMSRW-----EEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGR 3169
F + RW +E I KV + + ++G
Sbjct: 302 QRDKFL--KPSPRWRRGMSDEQILKVAKRKKS------------------------YRGI 335
Query: 3170 SYEEDMEIAEGCFRH--IKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAA 3343
E+ + +AE R+ IK+I L+E ++ ++ EA +I T + A
Sbjct: 336 PKEKIVSMAEWIIRNKKIKRIINNLDEIT---------EKIMNEILAEADVIVATNSMAG 386
Query: 3344 LKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPV 3523
+ + G+++D I+++E +Q +E IP++ + ++ IM GDH QLPP
Sbjct: 387 SE----ILKGWEFDVIVIDEGSQAMEPSCLIPIV---------KGRKLIMAGDHKQLPPT 433
Query: 3524 IKNMAFQKYSNMEQSLFTRFVRVGVPTVD--LDAQGRARASLCNL-----YNWRYKNLGN 3682
+ + ++++LF R ++ P L+ Q R + YN + K +
Sbjct: 434 V----LSENEELKKTLFERLIKK-YPEFSSILEIQYRMNEKIMEFPNKMFYNNKLKADES 488
Query: 3683 LPHVQLLP-----EFSTANAGLLYDF--QLINVEDFQGVGESEPNPYFYQNLGEAEYVVA 3841
+ ++ LL E + ++ + Q INVE + + P+ Y N+ EAE V+
Sbjct: 489 VKNITLLDLVKEEEIDEVDRDIINEIPVQFINVEGIERKDKESPS---YYNIEEAEKVLE 545
Query: 3842 LFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQND 4021
+ + P + ++T Y+ Q +R + +V TVD FQG++N+
Sbjct: 546 IVKKLVKYKIPTN---VITPYDAQVRYLRRLFEEH-------NIDIEVNTVDGFQGRENE 595
Query: 4022 YILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQ 4147
I++S VRT+ G L+D+RRL VA++RA+ L + +L +
Sbjct: 596 AIVISFVRTKNFGFLKDLRRLNVAITRAKRKLILIGNENLLK 637
>gi|172574|gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerevisiae]
Length = 2112
Score = 93.2 bits (230), Expect = 2e-17
Identities = 132/556 (23%), Positives = 229/556 (40%), Gaps = 49/556 (8%)
Frame = +2
Query: 2603 RNTIQFTHTQIEAI-RAGMQPGLTMVVGPPGTGKTDVAVQII------------------ 2725
+ + + +Q EAI + + G +++ GPPGTGKT + II
Sbjct: 1211 KKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVP 1270
Query: 2726 -----SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDF 2890
SN +Q+ LI SN A++++ ++ + D +
Sbjct: 1271 LEKNSSNTEQLLKKQKILICAPSNAAVDEICLRLKSGVYDKQGHQF----------KPQL 1320
Query: 2891 SRYGRVNYV-LARRIELLEEV--KRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYIS 3061
R GR + V +A + LEE+ KR+ G+ +Y T ++ ++ ++
Sbjct: 1321 VRVGRSDVVNVAIKDLTLEELVDKRI-------GERNYEIRTDP-----ELERKFNNAVT 1368
Query: 3062 KVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQL- 3238
K + L + N P+ ED+ + R + KI +L
Sbjct: 1369 KRRELRGKLDSES------------GNPESPMST-----EDISKLQLKIRELSKIINELG 1411
Query: 3239 ---EEFRASELLR---SGLDRSKYLLVKEAKIIAMT---CTHAALKRHD-LVKLGFKYDN 3388
+E R + LDR +A I+A++ C+ + HD L +G K+D
Sbjct: 1412 RDRDEMREKNSVNYRNRDLDRRN----AQAHILAVSDIICSTLSGSAHDVLATMGIKFDT 1467
Query: 3389 ILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQS 3568
++++EA Q E+ + IPL KR IM+GD +QLPP + + A + QS
Sbjct: 1468 VIIDEACQCTELSSIIPLRYGG--------KRCIMVGDPNQLPPTVLSGAASNF-KYNQS 1518
Query: 3569 LFTRFVRVGVPTVDLDAQGRARASLCNLYNWRY--KNLGNLPHVQLLPEFSTANAGLLYD 3742
LF R + P + LD Q R S+ + + L + P + +L + L
Sbjct: 1519 LFVRMEKNSSPYL-LDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAP 1577
Query: 3743 FQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMC-----LLGYPADKISILTTYN 3907
++ ++ G E Y N+ E + L Y+ + + KI I++ Y
Sbjct: 1578 YKFFDI--ISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDF-TGKIGIISPYR 1634
Query: 3908 GQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRT----RAVGHLRDV 4075
Q +R R G +I + T+D FQGQ+ + IL+S VR +VG L+D
Sbjct: 1635 EQMQKMRKEFARYFGG--MINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDF 1692
Query: 4076 RRLVVAMSRARLGLYI 4123
RR+ VA++RA+ +++
Sbjct: 1693 RRMNVALTRAKTSIWV 1708
>gi|6323462|ref|NP_013534.1| component of a nuclear-localized tRNA splicing complex; Sen1p
[Saccharomyces cerevisiae]
gi|3123282|sp|Q00416|SEN1_YEAST TRNA-SPLICING ENDONUCLEASE POSITIVE EFFECTOR
gi|1078364|pir||S53416 SEN1 protein - yeast (Saccharomyces cerevisiae)
gi|664872|gb|AAB67502.1| (U20939) Sen1p [Saccharomyces cerevisiae]
Length = 2231
Score = 93.2 bits (230), Expect = 2e-17
Identities = 132/556 (23%), Positives = 229/556 (40%), Gaps = 49/556 (8%)
Frame = +2
Query: 2603 RNTIQFTHTQIEAI-RAGMQPGLTMVVGPPGTGKTDVAVQII------------------ 2725
+ + + +Q EAI + + G +++ GPPGTGKT + II
Sbjct: 1330 KKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVP 1389
Query: 2726 -----SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDF 2890
SN +Q+ LI SN A++++ ++ + D +
Sbjct: 1390 LEKNSSNTEQLLKKQKILICAPSNAAVDEICLRLKSGVYDKQGHQF----------KPQL 1439
Query: 2891 SRYGRVNYV-LARRIELLEEV--KRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYIS 3061
R GR + V +A + LEE+ KR+ G+ +Y T ++ ++ ++
Sbjct: 1440 VRVGRSDVVNVAIKDLTLEELVDKRI-------GERNYEIRTDP-----ELERKFNNAVT 1487
Query: 3062 KVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQL- 3238
K + L + N P+ ED+ + R + KI +L
Sbjct: 1488 KRRELRGKLDSES------------GNPESPMST-----EDISKLQLKIRELSKIINELG 1530
Query: 3239 ---EEFRASELLR---SGLDRSKYLLVKEAKIIAMT---CTHAALKRHD-LVKLGFKYDN 3388
+E R + LDR +A I+A++ C+ + HD L +G K+D
Sbjct: 1531 RDRDEMREKNSVNYRNRDLDRRN----AQAHILAVSDIICSTLSGSAHDVLATMGIKFDT 1586
Query: 3389 ILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQS 3568
++++EA Q E+ + IPL KR IM+GD +QLPP + + A + QS
Sbjct: 1587 VIIDEACQCTELSSIIPLRYGG--------KRCIMVGDPNQLPPTVLSGAASNF-KYNQS 1637
Query: 3569 LFTRFVRVGVPTVDLDAQGRARASLCNLYNWRY--KNLGNLPHVQLLPEFSTANAGLLYD 3742
LF R + P + LD Q R S+ + + L + P + +L + L
Sbjct: 1638 LFVRMEKNSSPYL-LDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAP 1696
Query: 3743 FQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMC-----LLGYPADKISILTTYN 3907
++ ++ G E Y N+ E + L Y+ + + KI I++ Y
Sbjct: 1697 YKFFDI--ISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDF-TGKIGIISPYR 1753
Query: 3908 GQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRT----RAVGHLRDV 4075
Q +R R G +I + T+D FQGQ+ + IL+S VR +VG L+D
Sbjct: 1754 EQMQKMRKEFARYFGG--MINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDF 1811
Query: 4076 RRLVVAMSRARLGLYI 4123
RR+ VA++RA+ +++
Sbjct: 1812 RRMNVALTRAKTSIWV 1827
>gi|11595520|emb|CAC18314.1| (AL451022) probable HUPF1 protein [Neurospora crassa]
Length = 1093
Score = 92.8 bits (229), Expect = 3e-17
Identities = 84/282 (29%), Positives = 132/282 (46%), Gaps = 6/282 (2%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
+++ A ++ TC A R L K+ F+ N+L++E+ Q E E IPL+L
Sbjct: 591 ILQNADVVCCTCVGAGDPR--LSKMKFR--NVLIDESTQSAEPECMIPLVLG-------- 638
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNL- 3652
K+ +++GDH QL PVI N K + + QSLF R V++ + L Q R L
Sbjct: 639 CKQVVLVGDHKQLGPVIMNKKAAK-AGLNQSLFERLVKLQFTPIRLKVQYRMHPCLSEFP 697
Query: 3653 YNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESE--PNPYFYQNLGEA 3826
N Y+ G+L + E + + + + +G E + Y N EA
Sbjct: 698 SNMFYE--GSLQNGVTAAERLRKDVDFPWPVPETPMMFWSNLGNEEISASGTSYLNRTEA 755
Query: 3827 EYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQ 4006
V + G I ++T Y GQ+ I + + R +V +VD FQ
Sbjct: 756 ANVEKIVTRFFKAGVKPADIGVITPYEGQRSYIVNTMQNTGTFKKESYREVEVASVDAFQ 815
Query: 4007 GQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
G++ D+I+LS VR+ + +G L D RRL VA++RA+ GL I
Sbjct: 816 GREKDFIVLSCVRSNENQGIGFLSDPRRLNVALTRAKYGLVI 857
Score = 42.4 bits (98), Expect = 0.048
Identities = 29/89 (32%), Positives = 43/89 (47%), Gaps = 2/89 (2%)
Frame = +2
Query: 2552 EPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISN 2731
E V P + P + +QI AI+ + L+++ GPPGTGKT + I
Sbjct: 434 EVQVAPTKITMPKKFHVPGLPELNASQIAAIKQVLSNPLSLIQGPPGTGKTVTSATI--- 490
Query: 2732 IYH--NFPEQRTLIVTHSNQALNQLFEKI 2812
IYH + L+ SN A++QL E+I
Sbjct: 491 IYHLAKMSNSQVLVCAPSNVAVDQLCERI 519
>gi|6322835|ref|NP_012908.1| DNA helicase A; Hcs1p [Saccharomyces cerevisiae]
gi|465704|sp|P34243|YKB7_YEAST HYPOTHETICAL 78.3 KD PROTEIN IN RAM2-ATP7 INTERGENIC REGION
gi|422147|pir||S34700 probable purine nucleotide-binding protein YKL017c - yeast
(Saccharomyces cerevisiae)
gi|395256|emb|CAA52266.1| (X74152) orf4; homologous to human putative GTP-binding protein
[Saccharomyces cerevisiae]
gi|486007|emb|CAA81852.1| (Z28017) ORF YKL017c [Saccharomyces cerevisiae]
Length = 683
Score = 92.8 bits (229), Expect = 3e-17
Identities = 96/363 (26%), Positives = 167/363 (45%), Gaps = 30/363 (8%)
Frame = +2
Query: 3155 IFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKI---IAM 3325
I K S E D I E + +K + E + +LLR L + ++ +K+ I I +
Sbjct: 308 IVKDISQEIDKLIQEN--KKLKNYKQRKENWNEIKLLRKDLKKREFKTIKDLIIQSRIVV 365
Query: 3326 TCTHAALKRHDLVKL-----GFK-YDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRW 3487
T H + R +L L F+ +D ++++E +Q +E + +IPL+ Q+ F +L
Sbjct: 366 TTLHGSSSR-ELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAH--QNQFHKL--- 419
Query: 3488 IMIGDHHQLPPVIKNMAFQKY-SNMEQSLFTRFVRVGVPTVD----LDAQGRARASLC-- 3646
++ GD+ QLPP IK + N+E +LF R +++ P D L+ Q R +
Sbjct: 420 VLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIKI-FPKRDMVKFLNVQYRMNQKIMEF 478
Query: 3647 ---NLYNWRY--------KNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEP 3793
++YN + + L +LP V P + + + ++FQ +
Sbjct: 479 PSHSMYNGKLLADATVANRLLIDLPTVDATPSEDDDDTKIPLIWYDTQGDEFQETADEAT 538
Query: 3794 NPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGR 3973
N GE V + P + I +++ YN Q ++ +I+ +
Sbjct: 539 ILGSKYNEGEIAIVKEHIENLRSFNVPENSIGVISPYNAQVSHLKKLIHDELKLTDI--- 595
Query: 3974 PNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYIFARVSLF 4144
+++TVD FQG++ D I+LSLVR+ VG L++ RRL VAM+R R L + + +
Sbjct: 596 --EISTVDGFQGREKDVIILSLVRSNEKFEVGFLKEERRLNVAMTRPRRQLVVVGNIEVL 653
Query: 4145 QNC 4153
Q C
Sbjct: 654 QRC 656
Score = 47.4 bits (111), Expect = 0.001
Identities = 29/93 (31%), Positives = 47/93 (50%)
Frame = +2
Query: 2543 LIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQI 2722
L+ E IPN + + N +Q AI + LT++ GPPGTGKT +++
Sbjct: 184 LVNERPFIPNTNSFQNIKSFLNP-NLNDSQKTAINFAINNDLTIIHGPPGTGKTFTLIEL 242
Query: 2723 ISNIYHNFPEQRTLIVTHSNQALNQLFEKIMAL 2821
I + PE+R LI SN +++ + E++ L
Sbjct: 243 IQQLLIKNPEERILICGPSNISVDTILERLTPL 275
>gi|7488326|pir||T00533 SEN1 protein homolog T20K24.14 - Arabidopsis thaliana
gi|3176714|gb|AAD12029.1| (AC002392) putative DNA2-NAM7 helicase family protein [Arabidopsis
thaliana]
Length = 1090
Score = 92.0 bits (227), Expect = 5e-17
Identities = 100/367 (27%), Positives = 159/367 (43%), Gaps = 11/367 (2%)
Frame = +2
Query: 3191 IAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKL 3370
I EG FR LEE RAS L+ S EA+I+ T + + K +
Sbjct: 725 IVEGKFRAGNNF--NLEEARAS------LEAS---FANEAEIVFTTVSSSGRKLFSRLTH 773
Query: 3371 GFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKY 3550
GF D ++++EAAQ E+ PL L R +++GD QLP + + A
Sbjct: 774 GF--DMVVIDEAAQASEVGVLPPLALG--------AARCVLVGDPQQLPATVISKAAGTL 823
Query: 3551 SNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLL---PEFSTA 3721
+SLF RF G PT+ L Q R + + + RY G L + + P+
Sbjct: 824 L-YSRSLFERFQLAGCPTLLLTVQYRMHPQIRDFPS-RYFYQGRLKDSESISSAPDEIYY 881
Query: 3722 NAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYM--CLLGYPADKISI- 3892
+L + N+ G Y+N+ EA + V ++M++ L A K+S+
Sbjct: 882 KDPVLRPYLFFNIS--HGRESHRGGSVSYENVDEARFCVGVYMHLQKTLKSLGAGKVSVG 939
Query: 3893 -LTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRT--RAVGH 4063
+T Y Q ++ G + L + + TVD FQGQ+ D I++S VR VG
Sbjct: 940 VITPYKLQLKCLKHEFGNALGQDEL--KEIYINTVDAFQGQERDVIIMSCVRASGHGVGF 997
Query: 4064 LRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARP--LHLHIIPTEPFPTT 4237
+ D+RR+ VA++RAR L++ S + S R + + +P + FP
Sbjct: 998 VSDIRRMNVALTRARRALWVMGNASALMKSEDWAALISDARGRNCFMEMDSLPLD-FPIP 1056
Query: 4238 RKNGERP 4258
+ + P
Sbjct: 1057 KVSSYNP 1063
>gi|2340994|gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cerevisiae]
Length = 757
Score = 90.9 bits (224), Expect = 1e-16
Identities = 91/337 (27%), Positives = 152/337 (45%), Gaps = 22/337 (6%)
Frame = +2
Query: 3179 EDMEIAEGCFRHIKKIFTQL----EEFRASELLR---SGLDRSKYLLVKEAKIIAMT--- 3328
ED+ + R + KI +L +E R + LDR +A I+A++
Sbjct: 36 EDISKLQLKIRELSKIINELGRDRDEMREKNSVNYRNRDLDRRN----AQAHILAVSDII 91
Query: 3329 CTHAALKRHD-LVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDH 3505
C+ + HD L +G K+D ++++EA Q E+ + IPL KR IM+GD
Sbjct: 92 CSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGG--------KRCIMVGDP 143
Query: 3506 HQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRY--KNLG 3679
+QLPP + + A + QSLF R + P + LD Q R S+ + + L
Sbjct: 144 NQLPPTVLSGAASNF-KYNQSLFVRMEKNSSPYL-LDVQYRMHPSISKFPSSEFYQGRLK 201
Query: 3680 NLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMC 3859
+ P + +L + L ++ ++ G E Y N+ E + L Y+
Sbjct: 202 DGPGMDILNKRPWHQLEPLAPYKFFDI--ISGRQEQNAKTMSYTNMEEIRVAIELVDYLF 259
Query: 3860 -----LLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDY 4024
+ + KI I++ Y Q +R R G +I + T+D FQGQ+ +
Sbjct: 260 RKFDNKIDF-TGKIGIISPYREQMQKMRKEFARYFGG--MINKSIDFNTIDGFQGQEKEI 316
Query: 4025 ILLSLVRT----RAVGHLRDVRRLVVAMSRARLGLYI 4123
IL+S VR +VG L+D RR+ VA++RA+ +++
Sbjct: 317 ILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWV 353
>gi|1175495|sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTEIN C16C9.06C IN CHROMOSOME I
gi|2130283|pir||S62476 hypothetical protein SPAC16C9.06c - fission yeast
(Schizosaccharomyces pombe)
Length = 935
Score = 90.1 bits (222), Expect = 2e-16
Identities = 79/297 (26%), Positives = 133/297 (44%), Gaps = 21/297 (7%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L++ A +I TC A +R +K+ ++L++EA Q E E IPL+L
Sbjct: 544 LLRAAHVICCTCVGAGDRRISK----YKFRSVLIDEATQASEPECMIPLVLG-------- 591
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ +++GDH QL PV+ N +++ QSLF R + +G L Q R L
Sbjct: 592 AKQVVLVGDHQQLGPVVMNKKVA-LASLSQSLFERLIILGNSPFRLVVQYRMHPCLSEFP 650
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEY- 3832
+ + T G+ ++ DF + P FY N G+ E
Sbjct: 651 SNTFYE-------------GTLQNGVTTSERIARHVDFPWIQPDSPL-MFYANFGQEELS 696
Query: 3833 -----------------VVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNP 3961
+V F+ +L ++I I+T Y+GQ+ I +
Sbjct: 697 ASGTSFLNRTEASTCEKIVTTFLRSNVL---PEQIGIVTPYDGQRSYIVQYMQNNGSMQK 753
Query: 3962 LIGRPNKVTTVDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
+ + +V +VD FQG++ D+I+LS VR+ + +G + D RRL VA++RA+ G+ +
Sbjct: 754 DLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGVIV 810
Score = 44.7 bits (104), Expect = 0.010
Identities = 28/79 (35%), Positives = 43/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 2591 NQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQR---- 2758
N PK N +Q EA+RA + L+++ GPPGTGKT + ++ ++ +R
Sbjct: 399 NLPKLNA-----SQSEAVRAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHS 453
Query: 2759 -TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 454 PVLVCAPSNVAVDQLAEKI 472
>gi|7510904|pir||T27684 hypothetical protein ZK1067.2 - Caenorhabditis elegans
gi|3881525|emb|CAA93884.1| (Z70038) cDNA EST yk19a4.3 comes from this gene~cDNA EST yk19a4.5
comes from this gene~cDNA EST yk224b3.5 comes from this
gene~cDNA EST yk357f10.5 comes from this gene~cDNA EST
yk518c10.5 comes from this gene [Caenorhabditis elegans]
Length = 2219
Score = 90.1 bits (222), Expect = 2e-16
Identities = 85/320 (26%), Positives = 145/320 (44%), Gaps = 10/320 (3%)
Frame = +2
Query: 3233 QLEEFR-ASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAA 3409
Q+ E+R A E ++ +R +++ II T T + R L K+G + +++EEAA
Sbjct: 1182 QIREYREACENFKNAQNRVDAEIMRMTMIIGATTTGCSRLRPTLEKVGPRI--LIVEEAA 1239
Query: 3410 QILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVR 3589
++LE ++ S ++ +MIGDH QL P + S+F R V
Sbjct: 1240 EVLEAHIISAMI--------STVEHVVMIGDHKQLRPNPAVHELGVAYGLRISMFERLVE 1291
Query: 3590 VGVPTVDLDAQGRARASLCN--LYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVE 3763
G+P L Q R ++ + + Y N+ + +V L P+ L + + ++E
Sbjct: 1292 RGLPFSQLRQQHRMNLTISDKIVKLSFYDNVTDAENVGLYPDVQGMATNLFF-WSHTSME 1350
Query: 3764 DFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINR 3943
+ P+ + N E VAL ++ Y + I +L TY+ QK+L+
Sbjct: 1351 E-------SPDEVSWLNKHEISMTVALVKHLLKQNYTTNDIVVLATYSAQKNLMYREYAN 1403
Query: 3944 RCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR-------AVGHLRDVRRLVVAMSR 4102
G+ P V TVD FQG++ +++SLVR+ +G L R+ VA++R
Sbjct: 1404 VFGSTP-DSNVIPVETVDSFQGKERKIVIVSLVRSHRGGRENTGIGFLAVANRICVALTR 1462
Query: 4103 ARLGLYIFARVSLFQNCFEL 4162
A+ G+YI + N EL
Sbjct: 1463 AQHGMYIIGNGAYIMNNSEL 1482
Score = 42.0 bits (97), Expect = 0.063
Identities = 21/53 (39%), Positives = 31/53 (57%), Gaps = 4/53 (7%)
Frame = +2
Query: 2666 LTMVVGPPGTGKTDVAVQIISNIYHNFP----EQRTLIVTHSNQALNQLFEKI 2812
L+++ GPPGTGKT + VQI+ I N + L+V +N L+ L E+I
Sbjct: 825 LSLIQGPPGTGKTHIGVQIVKTILQNRSYWKITEPILVVCFTNSGLDNLLERI 877
>gi|7492892|pir||T37779 probable regulator of nonsense transcript stability - fission yeast
(Schizosaccharomyces pombe)
gi|4894186|emb|CAA91194.2| (Z54366) putative regulator of nonsense transcript stability
[Schizosaccharomyces pombe]
Length = 925
Score = 90.1 bits (222), Expect = 2e-16
Identities = 79/297 (26%), Positives = 133/297 (44%), Gaps = 21/297 (7%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L++ A +I TC A +R +K+ ++L++EA Q E E IPL+L
Sbjct: 534 LLRAAHVICCTCVGAGDRRISK----YKFRSVLIDEATQASEPECMIPLVLG-------- 581
Query: 3476 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 3655
K+ +++GDH QL PV+ N +++ QSLF R + +G L Q R L
Sbjct: 582 AKQVVLVGDHQQLGPVVMNKKVA-LASLSQSLFERLIILGNSPFRLVVQYRMHPCLSEFP 640
Query: 3656 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEY- 3832
+ + T G+ ++ DF + P FY N G+ E
Sbjct: 641 SNTFYE-------------GTLQNGVTTSERIARHVDFPWIQPDSPL-MFYANFGQEELS 686
Query: 3833 -----------------VVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNP 3961
+V F+ +L ++I I+T Y+GQ+ I +
Sbjct: 687 ASGTSFLNRTEASTCEKIVTTFLRSNVL---PEQIGIVTPYDGQRSYIVQYMQNNGSMQK 743
Query: 3962 LIGRPNKVTTVDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYI 4123
+ + +V +VD FQG++ D+I+LS VR+ + +G + D RRL VA++RA+ G+ +
Sbjct: 744 DLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGVIV 800
Score = 44.7 bits (104), Expect = 0.010
Identities = 28/79 (35%), Positives = 43/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 2591 NQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQR---- 2758
N PK N +Q EA+RA + L+++ GPPGTGKT + ++ ++ +R
Sbjct: 389 NLPKLNA-----SQSEAVRAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHS 443
Query: 2759 -TLIVTHSNQALNQLFEKI 2812
L+ SN A++QL EKI
Sbjct: 444 PVLVCAPSNVAVDQLAEKI 462
>gi|7486511|pir||T08986 hypothetical protein F6G3.130 - Arabidopsis thaliana
gi|4938486|emb|CAB43845.1| (AL078464) putative protein [Arabidopsis thaliana]
gi|7269910|emb|CAB81003.1| (AL161576) putative protein [Arabidopsis thaliana]
Length = 1311
Score = 89.7 bits (221), Expect = 3e-16
Identities = 93/344 (27%), Positives = 150/344 (43%), Gaps = 10/344 (2%)
Frame = +2
Query: 3191 IAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKL 3370
I EG FR LEE RAS L+ S EA+I+ T + + K +
Sbjct: 888 IVEGKFRAGTSF--NLEEARAS------LEAS---FANEAEIVFTTVSSSGRKLFSRLTH 936
Query: 3371 GFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKY 3550
GF D ++++EAAQ E+ PL L R +++GD QLP + + A
Sbjct: 937 GF--DMVVIDEAAQASEVGVLPPLALG--------AARCVLVGDPQQLPATVISKAAGTL 986
Query: 3551 SNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAG 3730
+SLF RF G PT+ L Q R + + + RY G L + + STA
Sbjct: 987 L-YSRSLFERFQLAGCPTLLLTVQYRMHPQIRDFPS-RYFYQGRLTDSESV---STAPDE 1041
Query: 3731 LLYDFQLINVEDFQGVGESEPN----PYFYQNLGEAEYVVALFMYMCL----LGYPADKI 3886
+ Y ++ F + + Y+N+ EA + V +++++ LG +
Sbjct: 1042 IYYKDSVLKPYLFFDISHGRESHRGGSVSYENIDEARFCVGVYLHLQRTLKSLGGGKVSV 1101
Query: 3887 SILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVR--TRAVG 4060
++T Y Q ++ + L + + TVD FQGQ+ D I++S VR VG
Sbjct: 1102 GVITPYKLQLKCLKIEFGNALSQDEL--QEIYINTVDAFQGQERDVIIMSCVRASNHGVG 1159
Query: 4061 HLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTAR 4192
+ D+RR+ VA++RA+ L++ S C + + AR
Sbjct: 1160 FVADIRRMNVALTRAKRALWVMGNASALMKCEDWAALITDAKAR 1203
>gi|9954728|gb|AAG09081.1|AC026237_2 (AC026237) Similar to tRNA-splicing endonuclease positive effector
SEN1 [Arabidopsis thaliana]
Length = 2142
Score = 87.4 bits (215), Expect = 1e-15
Identities = 140/601 (23%), Positives = 233/601 (38%), Gaps = 91/601 (15%)
Frame = +2
Query: 2618 FTHTQIEAIRAGMQPG-------LTMVVGPPGTGKTDVAVQIISNIY----HNFPEQRTL 2764
F +Q++AI + ++++ GPPGTGKT V IIS + H ++
Sbjct: 1197 FNESQLQAISVAIGSSNLMKAFDISLIQGPPGTGKTRTIVAIISGLLASASHKTSDRGNS 1256
Query: 2765 IVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRY---GRVNYVLARRIE 2935
HS+ Q +A+ T + + GRV + A+
Sbjct: 1257 EPGHSSSTSRQGMNPSVAVARAWQDAALAKQLNDNSETNRKIAEKNGRGRV-LICAQSNA 1315
Query: 2936 LLEEVKRLQKSLGV--------------PGDASYTCETAGYFFLYQVMS-RWEEYISKVK 3070
++E+ SLG+ G+A + FFL ++ R E ++
Sbjct: 1316 AVDELVSRISSLGIYGRDGKMFKPYLVRVGNAKTVHSNSMPFFLDTLVDQRLAEERMRIN 1375
Query: 3071 ----NKG--------STLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEE----------- 3181
NKG S L V + T F N K + E
Sbjct: 1376 ESKSNKGADSSALLRSNLEKVVDQITHFEAKRANINQESLDAKDKPENEHHNKDDDGKLM 1435
Query: 3182 -DMEIA---EGCFRHIKKIF-----TQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCT 3334
D E+ + +KI+ Q +E +A+ +R+ + + ++KEA+I+ T +
Sbjct: 1436 SDAELGIRLRRLYEQKRKIYKDLSAVQAQERKANYEMRTLKQKLRKSILKEAQIVVTTLS 1495
Query: 3335 HAALKRHDLV-------KLGFK-----YDNILMEEAAQILEIETFIPLLLQNPQDGFSRL 3478
+ + K G +D ++++EAAQ LE T IPL L SR
Sbjct: 1496 GCGGDLYSVCAESLAAHKFGSPSEDNLFDAVVIDEAAQALEPATLIPLQLLK-----SRG 1550
Query: 3479 KRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYN 3658
+ IM+GD QLP + + K+ E S+F R R G P + L Q R +C +
Sbjct: 1551 TKCIMVGDPKQLPATVLSNVASKFL-YECSMFERLQRAGYPILMLTQQYRMHPEICRFPS 1609
Query: 3659 WRYKNLGNLPHVQL----LPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEA 3826
+ + L V + P + G + +++ ++ + S N EA
Sbjct: 1610 MHFYDNKLLNGVDMSSKSAPFHENHHLGPYVFYDIVDGQEHRSGDSSS-----VCNEQEA 1664
Query: 3827 EYVVALFMYMCLLGYP----ADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTV 3994
E V L + YP A +I I+T Y Q ++R G + ++ TV
Sbjct: 1665 EAAVQLLRFF-KKRYPSEFVAGRIGIITPYKRQLAVLRSRFTGAFGAQ--VTADMEMNTV 1721
Query: 3995 DRFQGQQNDYILLSLVRT----------RAVGHLRDVRRLVVAMSRARLGLYIFARVSLF 4144
D FQG++ D ++LS VR +G + DVRR+ VA++RA+L L++
Sbjct: 1722 DGFQGKEVDILVLSTVRATHSAPDGVNQSRIGFVADVRRMNVALTRAKLSLWVLGNTRTL 1781
Query: 4145 Q 4147
Q
Sbjct: 1782 Q 1782
>gi|2842700|sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTEIN C6G9.10C IN CHROMOSOME I
gi|7490496|pir||T39072 DNA2-NAM7 helicase family protein - fission yeast
(Schizosaccharomyces pombe)
gi|1644322|emb|CAB03612.1| (Z81317) DNA2-NAM7 helicase family protein [Schizosaccharomyces
pombe]
Length = 1687
Score = 86.7 bits (213), Expect = 2e-15
Identities = 127/531 (23%), Positives = 200/531 (36%), Gaps = 24/531 (4%)
Frame = +2
Query: 2615 QFTHTQIEAIRAGMQP-GLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQAL 2791
Q Q +AI + G T++ GPPGTGKT + IIS + + +T NQ
Sbjct: 1129 QVNEPQAKAIMCALDNNGFTLIQGPPGTGKTKTIIGIISALLVDLSRYH---ITRPNQQS 1185
Query: 2792 NQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGRVNYVLARRIELLEEVKRLQKSL 2971
K L + V L R L K + + +
Sbjct: 1186 KSTESKQQIL-----------------LCAPSNAAVDEVLLRLKRGFLLENGEKYIPRVV 1228
Query: 2972 GVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQ 3151
+ + YQ + E + GS TF+ + +
Sbjct: 1229 RIGNPETINVSVRDLSLEYQTEKQLLEVNQGAIDLGSLQELTRWRDTFYDCIQKIEELEK 1288
Query: 3152 PIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTC 3331
I R ED + K++ ++ E +E L + KE ++
Sbjct: 1289 QIDVARDVAEDTKSLG------KELQNKINEKNLAEQKVEELQSQSFTKNKEVDLLRKKA 1342
Query: 3332 THAALKR------------HDLVK-LGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFS 3472
A LK+ HDLV + ++++EAAQ +E++T IPL
Sbjct: 1343 QKAILKQADVVCATLSGSGHDLVAHSSLNFSTVIIDEAAQAVELDTIIPLRYG------- 1395
Query: 3473 RLKRWIMIGDHHQLPPVI--KNMAFQKYSNMEQSLFTRFVR-VGVPTVDLDAQGRARASL 3643
K+ I++GD +QLPP + K A YS QSLF R + L Q R +
Sbjct: 1396 -AKKCILVGDPNQLPPTVLSKKAASLNYS---QSLFVRIQKNFSNQMCLLSIQYRMHPDI 1451
Query: 3644 CNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGE 3823
+ + ++ + L + E + + F + D +G E N NL E
Sbjct: 1452 SHFPSKKFYD-SRLEDGDNMAEKTQQVWHVNPKFTQYRLFDVRGK-ERTSNTMSTYNLEE 1509
Query: 3824 AEYVVALFMYMCLLGYP----ADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 3991
EY+V + + L +P +I ++T Y Q H +R + G + + + T
Sbjct: 1510 VEYLVNMVDEL-LNKFPDVNFTGRIGVITPYRSQLHELRRAFKVKYGKSFM--STIDIQT 1566
Query: 3992 VDRFQGQQNDYILLSLVRT---RAVGHLRDVRRLVVAMSRARLGLYIFARV 4135
VD FQGQ+ D I S V++ +G LRD RRL VA++RAR L I +
Sbjct: 1567 VDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSSLLIIGNM 1617
>gi|7301121|gb|AAF56255.1| (AE003746) CG6204 gene product [Drosophila melanogaster]
Length = 903
Score = 85.5 bits (210), Expect = 5e-15
Identities = 89/311 (28%), Positives = 138/311 (43%), Gaps = 21/311 (6%)
Frame = +2
Query: 3287 KYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDG 3466
++ L +E ++AMT T AA RH+ + + +L EEAA+I E L
Sbjct: 611 QFFLAREKDLLAMTTTCAA--RHNFLFRLLQSKCVLFEEAAEIQEAHIVACLT------- 661
Query: 3467 FSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQ-SLFTRFVRVGVPTVDLDAQGRARASL 3643
+ I++GDH QL P F + Q SLF R + G+P L+ Q R R+ +
Sbjct: 662 -PHTEHVILVGDHKQLQP------FSGSRKVPQISLFERLIVAGLPFSRLNLQYRMRSCI 714
Query: 3644 CNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLIN--VEDFQGVGESEPNPYFYQ-- 3811
L L+P +YD L + V++++ + N YF Q
Sbjct: 715 SEL---------------LVPS--------IYDELLCSESVKEYEDIRLMSKNLYFVQHN 751
Query: 3812 ------------NLGEAEYVVALFMYMCLLG-YPADKISILTTYNGQKHLIRDIINRRCG 3952
NL EA + L ++ Y I IL+ YNGQ I++ + +
Sbjct: 752 QPEHCMSDMSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYR 811
Query: 3953 NNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRA---VGHLRDVRRLVVAMSRARLGLYI 4123
+ +V +VD FQG + + +LLSLVR+ +G LR R+ VA+SRAR LYI
Sbjct: 812 STV------QVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYI 865
Query: 4124 FARVSLFQNCF 4156
V++ ++ F
Sbjct: 866 VGNVTILKDTF 876
Score = 41.2 bits (95), Expect = 0.11
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Frame = +2
Query: 2612 IQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRT---LIVTHSN 2782
+ +Q A + + +++ GPPGTGKT ++VQ+++++ N T +++T++N
Sbjct: 448 LHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTGPIIVLTYTN 507
Query: 2783 QALNQLFEKI 2812
+L++ KI
Sbjct: 508 NSLDKFLVKI 517
>gi|11359794|pir||T43280 nonsense-mediated mRNA decay trans-acting factor - Caenorhabditis
elegans
gi|3328177|gb|AAC26789.1| (AF074017) nonsense-mediated mRNA decay trans-acting factor
[Caenorhabditis elegans]
Length = 1069
Score = 82.8 bits (203), Expect = 3e-14
Identities = 76/285 (26%), Positives = 135/285 (46%), Gaps = 9/285 (3%)
Frame = +2
Query: 3296 LVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSR 3475
L+ A +I TC+ AA R ++ +L++E+ Q E E + ++
Sbjct: 580 LLAAADVICCTCSSAADARLSKIRTR----TVLIDESTQATEPEILVSIM--------RG 627
Query: 3476 LKRWIMIGDHHQLPPVI--KNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCN 3649
+++ +++GDH QL PV+ K A + + QSLF R V +G+ L Q R L
Sbjct: 628 VRQLVLVGDHCQLGPVVICKKAAI---AGLSQSLFERLVLLGIRPFRLQVQYRMHPVLSE 684
Query: 3650 LYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDF----QGVGESEPNPYFYQNL 3817
+ + + G+L + + E G+ + + N F G E + + N
Sbjct: 685 FPSNVFYD-GSLQNG--VTENDRHMTGVDWHWPKPNKPAFFWHCSGSEELSASGTSFLNR 741
Query: 3818 GEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVD 3997
EA V L + G +I ++T+Y GQ+ I + ++ + N + ++ +VD
Sbjct: 742 TEAANVEKLVSKLIKAGVQPHQIGVITSYEGQRSFIVNYMHTQGTLNSKLYENVEIASVD 801
Query: 3998 RFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYI 4123
FQG++ DYI+++ VR+ +G L D RRL VA++RA+ GL +
Sbjct: 802 AFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVL 846
Score = 43.5 bits (101), Expect = 0.022
Identities = 24/79 (30%), Positives = 47/79 (59%), Gaps = 4/79 (5%)
Frame = +2
Query: 2588 YNQPKRNTI----QFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQ 2755
++ P+R ++ + +Q++A++ + L+++ GPPGTGKT V+ I+ ++ E
Sbjct: 432 FDLPRRLSVAGLPELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSATIVYHLVQK-TEG 490
Query: 2756 RTLIVTHSNQALNQLFEKI 2812
L+ + SN A++ L EKI
Sbjct: 491 NVLVCSPSNIAVDHLAEKI 509
>gi|14738454|ref|XP_027828.1| KIAA0625 protein [Homo sapiens]
Length = 785
Score = 82.8 bits (203), Expect = 3e-14
Identities = 119/572 (20%), Positives = 229/572 (39%), Gaps = 51/572 (8%)
Frame = +2
Query: 2588 YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII-------------- 2725
+N+ ++ I+ + ++ + + ++ GPPGTGK+ V ++
Sbjct: 42 FNEDQKKAIETAYAMVK--HSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSD 99
Query: 2726 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGR 2905
N + R L+ SN A+++L +KI+
Sbjct: 100 ENSNAKIKQNRVLVCAPSNAAVDELMKKII------------------------------ 129
Query: 2906 VNYVLARRIELLEEVKRLQKSLGVPGDA---------SYTCETAGYFFLYQVMSRWEEYI 3058
+E E+ K + LG GD S E + QV R +
Sbjct: 130 --------LEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMK--- 178
Query: 3059 SKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQL 3238
K S + + + F + + + + +G + E+ E +I K+ +
Sbjct: 179 ---KELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDE----NISKVSKER 231
Query: 3239 EEFRAS-ELLRSGLDRSKYLLVKEAKIIAMTCTHAA---LKRHDLVKLGFKYDNILMEEA 3406
+E + + ++ +++ +++ E+ II T + + L+ + G + ++++EA
Sbjct: 232 QELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 291
Query: 3407 AQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFV 3586
Q EIET PL+ R + I++GD QLPP + +M Q+Y +QS+ RF
Sbjct: 292 GQSCEIETLTPLI--------HRCNKLILVGDPKQLPPTVISMKAQEYG-YDQSMMARFC 342
Query: 3587 RV-----------GVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGL 3733
R+ +P + L Q R +C L+ Y NL + ++
Sbjct: 343 RLLEENVEHNMISRLPILQLTVQYRMHPDIC-LFPSNYVYNRNLKTNRQTEAIRCSSDWP 401
Query: 3734 LYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADK--------IS 3889
+ + +V D G + Y N+ E + V+ + + DK I
Sbjct: 402 FQPYLVFDVGD----GSERRDNDSYINVQEIKLVMEIIKLI------KDKRKDVSFRNIG 451
Query: 3890 ILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR----AV 4057
I+T Y QK +I+ +++ P +V TVD FQG+Q D ++++ VR ++
Sbjct: 452 IITHYKAQKTMIQKDLDKEFDRKG----PAEVDTVDAFQGRQKDCVIVTCVRANSIQGSI 507
Query: 4058 GHLRDVRRLVVAMSRARLGLYIFARV-SLFQN 4150
G L ++RL V ++RA+ L+I + +L +N
Sbjct: 508 GFLASLQRLNVTITRAKYSLFILGHLRTLMEN 539
>gi|3327064|dbj|BAA31600.1| (AB014525) KIAA0625 protein [Homo sapiens]
Length = 791
Score = 82.8 bits (203), Expect = 3e-14
Identities = 119/572 (20%), Positives = 229/572 (39%), Gaps = 51/572 (8%)
Frame = +2
Query: 2588 YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII-------------- 2725
+N+ ++ I+ + ++ + + ++ GPPGTGK+ V ++
Sbjct: 48 FNEDQKKAIETAYAMVK--HSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSD 105
Query: 2726 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGR 2905
N + R L+ SN A+++L +KI+
Sbjct: 106 ENSNAKIKQNRVLVCAPSNAAVDELMKKII------------------------------ 135
Query: 2906 VNYVLARRIELLEEVKRLQKSLGVPGDA---------SYTCETAGYFFLYQVMSRWEEYI 3058
+E E+ K + LG GD S E + QV R +
Sbjct: 136 --------LEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMK--- 184
Query: 3059 SKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQL 3238
K S + + + F + + + + +G + E+ E +I K+ +
Sbjct: 185 ---KELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDE----NISKVSKER 237
Query: 3239 EEFRAS-ELLRSGLDRSKYLLVKEAKIIAMTCTHAA---LKRHDLVKLGFKYDNILMEEA 3406
+E + + ++ +++ +++ E+ II T + + L+ + G + ++++EA
Sbjct: 238 QELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 297
Query: 3407 AQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFV 3586
Q EIET PL+ R + I++GD QLPP + +M Q+Y +QS+ RF
Sbjct: 298 GQSCEIETLTPLI--------HRCNKLILVGDPKQLPPTVISMKAQEYG-YDQSMMARFC 348
Query: 3587 RV-----------GVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGL 3733
R+ +P + L Q R +C L+ Y NL + ++
Sbjct: 349 RLLEENVEHNMISRLPILQLTVQYRMHPDIC-LFPSNYVYNRNLKTNRQTEAIRCSSDWP 407
Query: 3734 LYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADK--------IS 3889
+ + +V D G + Y N+ E + V+ + + DK I
Sbjct: 408 FQPYLVFDVGD----GSERRDNDSYINVQEIKLVMEIIKLI------KDKRKDVSFRNIG 457
Query: 3890 ILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR----AV 4057
I+T Y QK +I+ +++ P +V TVD FQG+Q D ++++ VR ++
Sbjct: 458 IITHYKAQKTMIQKDLDKEFDRKG----PAEVDTVDAFQGRQKDCVIVTCVRANSIQGSI 513
Query: 4058 GHLRDVRRLVVAMSRARLGLYIFARV-SLFQN 4150
G L ++RL V ++RA+ L+I + +L +N
Sbjct: 514 GFLASLQRLNVTITRAKYSLFILGHLRTLMEN 545
>gi|7662212|ref|NP_055861.1| KIAA0625 protein [Homo sapiens]
gi|14738442|ref|XP_027830.1| KIAA0625 protein [Homo sapiens]
gi|7022724|dbj|BAA91701.1| (AK001456) unnamed protein product [Homo sapiens]
Length = 828
Score = 82.8 bits (203), Expect = 3e-14
Identities = 119/572 (20%), Positives = 229/572 (39%), Gaps = 51/572 (8%)
Frame = +2
Query: 2588 YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII-------------- 2725
+N+ ++ I+ + ++ + + ++ GPPGTGK+ V ++
Sbjct: 85 FNEDQKKAIETAYAMVK--HSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSD 142
Query: 2726 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDXXXXXXXXXXXXXXXTEKDFSRYGR 2905
N + R L+ SN A+++L +KI+
Sbjct: 143 ENSNAKIKQNRVLVCAPSNAAVDELMKKII------------------------------ 172
Query: 2906 VNYVLARRIELLEEVKRLQKSLGVPGDA---------SYTCETAGYFFLYQVMSRWEEYI 3058
+E E+ K + LG GD S E + QV R +
Sbjct: 173 --------LEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMK--- 221
Query: 3059 SKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQL 3238
K S + + + F + + + + +G + E+ E +I K+ +
Sbjct: 222 ---KELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDE----NISKVSKER 274
Query: 3239 EEFRAS-ELLRSGLDRSKYLLVKEAKIIAMTCTHAA---LKRHDLVKLGFKYDNILMEEA 3406
+E + + ++ +++ +++ E+ II T + + L+ + G + ++++EA
Sbjct: 275 QELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 334
Query: 3407 AQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFV 3586
Q EIET PL+ R + I++GD QLPP + +M Q+Y +QS+ RF
Sbjct: 335 GQSCEIETLTPLI--------HRCNKLILVGDPKQLPPTVISMKAQEYG-YDQSMMARFC 385
Query: 3587 RV-----------GVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGL 3733
R+ +P + L Q R +C L+ Y NL + ++
Sbjct: 386 RLLEENVEHNMISRLPILQLTVQYRMHPDIC-LFPSNYVYNRNLKTNRQTEAIRCSSDWP 444
Query: 3734 LYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADK--------IS 3889
+ + +V D G + Y N+ E + V+ + + DK I
Sbjct: 445 FQPYLVFDVGD----GSERRDNDSYINVQEIKLVMEIIKLI------KDKRKDVSFRNIG 494
Query: 3890 ILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR----AV 4057
I+T Y QK +I+ +++ P +V TVD FQG+Q D ++++ VR ++
Sbjct: 495 IITHYKAQKTMIQKDLDKEFDRKG----PAEVDTVDAFQGRQKDCVIVTCVRANSIQGSI 550
Query: 4058 GHLRDVRRLVVAMSRARLGLYIFARV-SLFQN 4150
G L ++RL V ++RA+ L+I + +L +N
Sbjct: 551 GFLASLQRLNVTITRAKYSLFILGHLRTLMEN 582
>gi|6321958|ref|NP_012034.1| DNA replication helicase; Dna2p [Saccharomyces cerevisiae]
gi|731738|sp|P38859|DNA2_YEAST DNA REPLICATION HELICASE DNA2
gi|626832|pir||S48904 probable purine nucleotide-binding protein YHR164c - yeast
(Saccharomyces cerevisiae)
gi|458906|gb|AAB68010.1| (U00027) Dna2p: DNA replication helicase [Saccharomyces cerevisiae]
Length = 1522
Score = 82.0 bits (201), Expect = 5e-14
Identities = 88/328 (26%), Positives = 145/328 (43%), Gaps = 30/328 (9%)
Frame = +2
Query: 3299 VKEAKIIAMTCTHAALKRHDLV-KLGFK-YDNILMEEAAQILEIETFIPLLLQNPQDGFS 3472
+ ++A TC L +D++ L K +D ++++EA+QI PL N
Sbjct: 1155 INSTSVVATTC----LGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGN------ 1204
Query: 3473 RLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTV-DLDAQGRARASLCN 3649
R+IM+GDH+QLPP++KN A + +E+SLF F +V +L Q R +
Sbjct: 1205 ---RFIMVGDHYQLPPLVKNDA-ARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVT 1260
Query: 3650 LYNWR-YKN---LGN---------LPHVQLLPEFSTANAGLLYDFQ----------LINV 3760
L N+ Y N GN LP + L + +A + +N
Sbjct: 1261 LSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRKVVFLNY 1320
Query: 3761 EDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIIN 3940
++ + E N GEAE + M L G P + I ++T Y Q L++ I N
Sbjct: 1321 DNCPDIIEQSEKDNI-TNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFN 1379
Query: 3941 RRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAV----GHLRDVRRLVVAMSRAR 4108
+ + ++ T D+FQG+ I++S+VR + L+++RR+ VAM+RA+
Sbjct: 1380 KNVYDG------LEILTADQFQGRDKKCIIISMVRRNSQLNGGALLKELRRVNVAMTRAK 1433
Query: 4109 LGLYIFARVSLFQNCFELTPAFSQLTAR 4192
L I S + E+ + L R
Sbjct: 1434 SKLIIIGSKSTIGSVPEIKSFVNLLEER 1461
>gi|2506893|sp|P51530|DN2L_HUMAN DNA2-LIKE HOMOLOG (DNA REPLICATION HELICASE-LIKE HOMOLOG)
gi|11360302|pir||T50697 hypothetical protein KIAA0083 [imported] - human (fragment)
gi|1531548|dbj|BAA07647.1| (D42046) The ha3631 gene product is related to S.cerevisiae protein
encoded in chromosome VIII. [Homo sapiens]
Length = 1077
Score = 81.3 bits (199), Expect = 9e-14
Identities = 97/348 (27%), Positives = 152/348 (42%), Gaps = 34/348 (9%)
Frame = +2
Query: 3215 IKKIFTQLEEFRASELLRSGLDRSKYLLVK---EAKIIAMTC---THAALKRHDLVKLGF 3376
I+K+ +++F E+ RS +S LL + I+A TC H R
Sbjct: 719 IQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKI------ 772
Query: 3377 KYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSN 3556
+D +++EA+QI + PL FSR R++++GDH QLPP++ N +
Sbjct: 773 -FDFCIVDEASQISQPICLGPLF-------FSR--RFVLVGDHQQLPPLVLNREARALG- 821
Query: 3557 MEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYN-WRYK---------------NLGNLP 3688
M +SLF R + V L Q R + + +L N Y+ NL +
Sbjct: 822 MSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFK 881
Query: 3689 HVQLLPEFS---TANAGLLYDFQLINVEDFQGVGESEPNPYFYQ-----NLGEAEYVVAL 3844
V+L EF + N L+ F+ N F + P P + N+ EA+ +V L
Sbjct: 882 DVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT-DKVPAPEQVEKGGVSNVTEAKLIVFL 940
Query: 3845 FMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDY 4024
G I I+ Y Q +I D++ R G +V TVD++QG+
Sbjct: 941 TSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMV-------EVNTVDKYQGRDKSI 993
Query: 4025 ILLSLVRTRAVGH----LRDVRRLVVAMSRARLGLYIFARVSLFQNCF 4156
+L+S VR+ G L+D RRL VA++RA+ L + V NC+
Sbjct: 994 VLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL-NCY 1040
>gi|14748403|ref|XP_052298.1| DNA2 (DNA replication helicase, yeast, homolog)-like [Homo sapiens]
Length = 576
Score = 81.3 bits (199), Expect = 9e-14
Identities = 97/348 (27%), Positives = 152/348 (42%), Gaps = 34/348 (9%)
Frame = +2
Query: 3215 IKKIFTQLEEFRASELLRSGLDRSKYLLVK---EAKIIAMTC---THAALKRHDLVKLGF 3376
I+K+ +++F E+ RS +S LL + I+A TC H R
Sbjct: 218 IQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKI------ 271
Query: 3377 KYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSN 3556
+D +++EA+QI + PL FSR R++++GDH QLPP++ N +
Sbjct: 272 -FDFCIVDEASQISQPICLGPLF-------FSR--RFVLVGDHQQLPPLVLNREARALG- 320
Query: 3557 MEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYN-WRYK---------------NLGNLP 3688
M +SLF R + V L Q R + + +L N Y+ NL +
Sbjct: 321 MSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFK 380
Query: 3689 HVQLLPEFS---TANAGLLYDFQLINVEDFQGVGESEPNPYFYQ-----NLGEAEYVVAL 3844
V+L EF + N L+ F+ N F + P P + N+ EA+ +V L
Sbjct: 381 DVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT-DKVPAPEQVEKGGVSNVTEAKLIVFL 439
Query: 3845 FMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDY 4024
G I I+ Y Q +I D++ R G +V TVD++QG+
Sbjct: 440 TSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMV-------EVNTVDKYQGRDKSI 492
Query: 4025 ILLSLVRTRAVGH----LRDVRRLVVAMSRARLGLYIFARVSLFQNCF 4156
+L+S VR+ G L+D RRL VA++RA+ L + V NC+
Sbjct: 493 VLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL-NCY 539
>gi|7446667|pir||G72429 hypothetical protein TM0005 - Thermotoga maritima (strain MSB8)
gi|4980488|gb|AAD35099.1|AE001689_5 (AE001689) DNA helicase, putative [Thermotoga maritima]
Length = 650
Score = 80.5 bits (197), Expect = 2e-13
Identities = 87/338 (25%), Positives = 161/338 (46%), Gaps = 22/338 (6%)
Frame = +2
Query: 3161 KGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHA 3340
+G S E+ E+AE K+ +Q+++ R +L+ + +V+EA+++ T + A
Sbjct: 315 RGVSKEKIKEMAEWI-----KLNSQIQDIR--DLIERKEEIIASRIVREAQVVLSTNSSA 367
Query: 3341 ALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPP 3520
AL+ + G +D ++++EA+Q IP+ S+ K++++ GDH QLPP
Sbjct: 368 ALE----ILSGIVFDVVVVDEASQATIPSILIPI---------SKGKKFVLAGDHKQLPP 414
Query: 3521 VIKNMAFQKYSNMEQSLFTRFV-RVGVPTVDLDAQGRARASLC-----NLYNWRYKNLGN 3682
I + + ++ ++LF + R + LD Q R L Y+ + K
Sbjct: 415 TILS---EDAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEK 471
Query: 3683 LPHVQLLP-EFSTANAGLLYDFQLI--NV----------EDFQGVGESEPNPYFYQNLGE 3823
+ ++ L N G +D L NV + F+ + P+ +N E
Sbjct: 472 VRNITLFDLGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPS---RENPLE 528
Query: 3824 AEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRF 4003
A+ V + + +G D I I+T Y+ Q +LIR++I + +V +VD F
Sbjct: 529 AQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKV----------EVHSVDGF 578
Query: 4004 QGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRAR 4108
QG++ + I++S VR+ +G L D+RRL V+++RA+
Sbjct: 579 QGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAK 616
Database: nr
Posted date: Jul 30, 2001 8:58 PM
Number of letters in database: 230,545,999
Number of sequences in database: 727,771
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,491,134,110
Number of Sequences: 727771
Number of extensions: 55743594
Number of successful extensions: 159471
Number of sequences better than 10.0: 438
Number of HSP's better than 10.0 without gapping: 125403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 158024
length of database: 230,545,999
effective HSP length: 134
effective length of database: 133,024,685
effective search space used: 244366346345
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)