Score E
Sequences producing significant alignments: (bits) Value
gi|7706351|ref|NP_057161.1| CGI-147 protein [Homo sapiens] ... 222 1e-57
gi|11359891|pir||T46479 hypothetical protein DKFZp434A1535.... 222 1e-57
gi|6728991|gb|AAF26989.1|AC018363_34 (AC018363) unknown pro... 126 1e-28
gi|9438135|gb|AAF87580.1|AF275673_1 (AF275673) unknown [Aed... 125 2e-28
gi|6686186|sp|O13830|YEEE_SCHPO HYPOTHETICAL 21.4 KDA PROTE... 125 3e-28
gi|11359529|pir||T49644 hypothetical protein B5O22.260 [imp... 124 4e-28
gi|11357729|pir||T51542 hypothetical protein F2K13_20 - Ara... 124 6e-28
gi|6686163|sp|O97067|YCE7_DROME HYPOTHETICAL 18.8 KDA PROTE... 119 1e-26
gi|7298895|gb|AAF54101.1| (AE003674) BG:DS00004.12 gene pro... 119 1e-26
gi|6319414|ref|NP_009496.1| Ybl057cp [Saccharomyces cerevis... 117 7e-26
gi|14520837|ref|NP_126312.1| hypothetical protein [Pyrococc... 112 1e-24
gi|14591321|ref|NP_143399.1| hypothetical protein [Pyrococc... 109 1e-23
gi|13813307|gb|AAK40521.1| (AE006655) Conserved hypothetica... 107 4e-23
gi|2495766|sp|Q60363|Y051_METJA HYPOTHETICAL PROTEIN MJ0051... 105 2e-22
gi|6686188|sp|O27732|YG97_METTH HYPOTHETICAL PROTEIN MTH169... 96 2e-19
gi|8248747|emb|CAB62849.2| (AL035475) conserved hypothetica... 92 2e-18
gi|10639254|emb|CAC11256.1| (AL445063) conserved hypothetic... 92 2e-18
gi|13541018|ref|NP_110706.1| Uncharacterized conserved prot... 89 2e-17
gi|14601543|ref|NP_148083.1| hypothetical protein [Aeropyru... 88 4e-17
gi|11499678|ref|NP_070920.1| conserved hypothetical protein... 87 8e-17
gi|6686094|sp|O76387|Y248_CAEEL HYPOTHETICAL 33.7 KDA PROTE... 83 1e-15
gi|9634699|ref|NP_038992.1| ORF FPV029 Conserved hypothetic... 76 1e-13
gi|7486213|pir||T05298 hypothetical protein F26P21.20 - Ara... 60 1e-08
gi|7479353|pir||T34684 hypothetical protein SC1B5.06c - Str... 37 0.071
gi|11349250|pir||F83446 hypothetical protein PA1593 [import... 33 1.0
gi|2497556|sp|Q25410|MIPR_LYMST PUTATIVE MOLLUSCAN INSULIN-... 33 1.3
gi|6754362|ref|NP_035962.1| insulin receptor-related recept... 33 1.7
gi|7293999|gb|AAF49356.1| (AE003524) CG13727 gene product [... 33 1.7
gi|12644000|sp|P14616|IRR_HUMAN INSULIN RECEPTOR-RELATED PR... 32 2.3
gi|106736|pir||B36502 insulin receptor-related receptor - h... 32 2.3
gi|186555|gb|AAC31759.1| (J05046) insulin receptor-related ... 32 2.3
gi|1019792|emb|CAA91187.1| (Z54364) vicilin [Matteuccia str... 32 3.0
gi|12516819|gb|AAG57556.1|AE005474_4 (AE005474) orf, hypoth... 31 5.1
gi|2497553|sp||IRR_RAT_1 [Segment 1 of 2] INSULIN RECEPTOR-... 31 6.6
gi|11559992|ref|NP_071548.1| insulin receptor-related recep... 31 6.6
gi|2117842|pir||B47417 insulin receptor-related receptor, s... 31 6.6
gi|425789|dbj|BAA03068.1| (D13965) sIRR-1 [Rattus norvegicus] 31 6.6
gi|13517025|dbj|BAB40395.1| (AB047172) DNA gyrase B subunit... 30 8.7
gi|13517031|dbj|BAB40398.1| (AB047175) DNA gyrase B subunit... 30 8.7
gi|124908|sp|P14617|IRR_CAVPO INSULIN RECEPTOR-RELATED PROT... 30 8.7
gi|112516|pir||A36502 insulin receptor-related receptor pre... 30 8.7
Alignments
>gi|7706351|ref|NP_057161.1| CGI-147 protein [Homo sapiens]
gi|11525859|ref|XP_008309.1| CGI-147 protein [Homo sapiens]
gi|14772016|ref|XP_027789.1| CGI-147 protein [Homo sapiens]
gi|6686183|sp|Q9Y3E5|YCE7_HUMAN HYPOTHETICAL PROTEIN CGI-147
gi|4929763|gb|AAD34142.1|AF151905_1 (AF151905) CGI-147 protein [Homo sapiens]
gi|13905048|gb|AAH06807.1|AAH06807 (BC006807) CGI-147 protein [Homo sapiens]
Length = 179
Score = 222 bits (566), Expect = 1e-57
Identities = 115/139 (82%), Positives = 119/139 (84%)
Frame = -3
Query: 552 PKAGRAGTHXS*K*SRHLGRQPGSPG*FLVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRR 373
PK+ + TH + + G LVVR DLKMGKGKVAAQCSHAAVSAYKQIQRR
Sbjct: 41 PKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRR 100
Query: 372 NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG 193
NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG
Sbjct: 101 NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG 160
Query: 192 IGPGPADLIDKVTGHLKLY 136
IGPGPADLIDKVTGHLKLY
Sbjct: 161 IGPGPADLIDKVTGHLKLY 179
>gi|11359891|pir||T46479 hypothetical protein DKFZp434A1535.1 - human (fragment)
gi|6807813|emb|CAB70696.1| (AL137322) hypothetical protein [Homo sapiens]
Length = 176
Score = 222 bits (566), Expect = 1e-57
Identities = 115/139 (82%), Positives = 119/139 (84%)
Frame = -3
Query: 552 PKAGRAGTHXS*K*SRHLGRQPGSPG*FLVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRR 373
PK+ + TH + + G LVVR DLKMGKGKVAAQCSHAAVSAYKQIQRR
Sbjct: 38 PKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRR 97
Query: 372 NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG 193
NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG
Sbjct: 98 NPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLG 157
Query: 192 IGPGPADLIDKVTGHLKLY 136
IGPGPADLIDKVTGHLKLY
Sbjct: 158 IGPGPADLIDKVTGHLKLY 176
>gi|6728991|gb|AAF26989.1|AC018363_34 (AC018363) unknown protein [Arabidopsis thaliana]
Length = 179
Score = 126 bits (316), Expect = 1e-28
Identities = 64/110 (58%), Positives = 79/110 (71%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DLKMGKGK+AAQCSHA + YK++ +R P+ L +WEYC QPKVVVK EE ++
Sbjct: 70 LVVRNDLKMGKGKIAAQCSHATLGLYKKLLQRAPKALNRWEYCAQPKVVVKIESEEEMLV 129
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
L AK L L + DAG+TQIAP S+TV+ I GP D +D+VTG LKL
Sbjct: 130 LQERAKTLKLPTHITIDAGKTQIAPNSRTVMAI-LGPVDNVDEVTGGLKL 178
>gi|9438135|gb|AAF87580.1|AF275673_1 (AF275673) unknown [Aedes triseriatus]
Length = 174
Score = 125 bits (315), Expect = 2e-28
Identities = 60/110 (54%), Positives = 79/110 (71%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DLKMGKGK+AAQC HAAV A++ ++ P +L++W++ GQ K+ VK +E+ L+
Sbjct: 64 LVVRNDLKMGKGKIAAQCGHAAVGAFEGALKKTPSVLRKWQHTGQAKIAVKVENEQQLME 123
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ AK L LI+DAGRTQI P S+TVL IGP P +ID +TGHLKL
Sbjct: 124 VYRTAKANNLNCCLIRDAGRTQIEPNSKTVLAIGPAPNQVIDMITGHLKL 173
>gi|6686186|sp|O13830|YEEE_SCHPO HYPOTHETICAL 21.4 KDA PROTEIN C19A8.14 IN CHROMOSOME I
gi|7490892|pir||T37947 hypothetical protein SPAC19A8.14 - fission yeast
(Schizosaccharomyces pombe)
gi|2388913|emb|CAB11650.1| (Z98974) hypothetical protein [Schizosaccharomyces pombe]
Length = 205
Score = 125 bits (313), Expect = 3e-28
Identities = 63/111 (56%), Positives = 80/111 (71%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DL M KGK+AAQC+HAA++ YK +P++++ WE GQ K+ ++A EETL
Sbjct: 95 LVVRTDLGMTKGKIAAQCAHAALACYKIASAVDPDLVRIWENAGQAKITLQAQTEETLEL 154
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY 136
L A A LGL +I DAGRTQIA GS TVLGIGPGP +I++VTG LKL+
Sbjct: 155 LQAQAMSLGLCARVIHDAGRTQIASGSATVLGIGPGPVSVINEVTGSLKLF 205
>gi|11359529|pir||T49644 hypothetical protein B5O22.260 [imported] - Neurospora crassa
gi|7801049|emb|CAB91445.1| (AL355932) conserved hypothetical protein [Neurospora crassa]
Length = 330
Score = 124 bits (311), Expect = 4e-28
Identities = 61/118 (51%), Positives = 83/118 (69%), Gaps = 8/118 (6%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRR--------NPEMLKQWEYCGQPKVVVKA 313
LVVR DL M KGK+AAQCSHA ++ YK++ + +L+QWE GQ K+ V+
Sbjct: 212 LVVRTDLGMTKGKIAAQCSHATLACYKRLFSAAQLEPLSLSARLLRQWERNGQAKIAVQT 271
Query: 312 PDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
E+ ++ L+A A+ LG+T +IQDAGRTQIA GS+TVLG+GP P L+D++TGHLKL
Sbjct: 272 KTEDEMLELMAKARSLGVTAEVIQDAGRTQIASGSRTVLGVGPAPKSLVDEITGHLKL 329
>gi|11357729|pir||T51542 hypothetical protein F2K13_20 - Arabidopsis thaliana
gi|9755688|emb|CAC01700.1| (AL391141) putative protein [Arabidopsis thaliana]
Length = 174
Score = 124 bits (310), Expect = 6e-28
Identities = 64/114 (56%), Positives = 79/114 (69%), Gaps = 4/114 (3%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DLKMGKGK+AAQCSHA + YK++ RR P+ L WE C QPKVVVK DE+ ++
Sbjct: 60 LVVRNDLKMGKGKIAAQCSHATLGLYKKLVRRAPKALDCWEECAQPKVVVKIEDEDEMLE 119
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGI----GPGPADLIDKVTGHLKL 139
L AK L L + DAGRTQIAP S+TV+ I GP +++D+VTG LKL
Sbjct: 120 LQERAKSLKLPTHITIDAGRTQIAPNSRTVMAILDFTSAGPVEVVDEVTGGLKL 173
>gi|6686163|sp|O97067|YCE7_DROME HYPOTHETICAL 18.8 KDA PROTEIN BG:DS00004.12
gi|4389444|gb|AAD19814.1| (AE001572) hypothetical 23.1kd-like protein [Drosophila
melanogaster]
Length = 176
Score = 119 bits (299), Expect = 1e-26
Identities = 60/110 (54%), Positives = 74/110 (66%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DLKMGKGK+AAQC H AV AY++ R P +L+ WE CG K+ V+ E L+A
Sbjct: 66 LVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAELMA 125
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A+ L LI+DAGRTQI S+TVL +GP A ID+VTGHLKL
Sbjct: 126 IKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKL 175
>gi|7298895|gb|AAF54101.1| (AE003674) BG:DS00004.12 gene product [Drosophila melanogaster]
Length = 186
Score = 119 bits (299), Expect = 1e-26
Identities = 60/110 (54%), Positives = 74/110 (66%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
LVVR DLKMGKGK+AAQC H AV AY++ R P +L+ WE CG K+ V+ E L+A
Sbjct: 76 LVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAELMA 135
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A+ L LI+DAGRTQI S+TVL +GP A ID+VTGHLKL
Sbjct: 136 IKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKL 185
>gi|6319414|ref|NP_009496.1| Ybl057cp [Saccharomyces cerevisiae]
gi|465516|sp|P34222|YBF7_YEAST HYPOTHETICAL 23.1 KDA PROTEIN IN SHP1-PTC3 INTERGENIC REGION
gi|542310|pir||S39831 hypothetical protein YBL057c - yeast (Saccharomyces cerevisiae)
gi|313741|emb|CAA80790.1| (Z23261) YBLO514 [Saccharomyces cerevisiae]
gi|536088|emb|CAA84877.1| (Z35818) ORF YBL057c [Saccharomyces cerevisiae]
Length = 214
Score = 117 bits (292), Expect = 7e-26
Identities = 63/131 (48%), Positives = 82/131 (62%), Gaps = 6/131 (4%)
Frame = -3
Query: 510 SRHLGRQPGSPG*FLVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRR------NPEMLKQW 349
S L PG LV+R DL M KGK+AAQC HAA+S ++ I NP M ++W
Sbjct: 84 STSLNDIPGEVRMALVIRQDLGMTKGKIAAQCCHAALSCFRHIATNPARASYNPIMTQRW 143
Query: 348 EYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADL 169
GQ K+ +K PD+ T+ L A A LG+ ++I DAGRTQIA GS TVLG+GP P +
Sbjct: 144 LNAGQAKITLKCPDKFTMDELYAKAISLGVNAAVIHDAGRTQIAAGSATVLGLGPAPKAV 203
Query: 168 IDKVTGHLKLY 136
+D++TG LKLY
Sbjct: 204 LDQITGDLKLY 214
>gi|14520837|ref|NP_126312.1| hypothetical protein [Pyrococcus abyssi]
gi|7517850|pir||H75182 hypothetical protein PAB0429 - Pyrococcus abyssi (strain Orsay)
gi|5458053|emb|CAB49543.1| (AJ248284) hypothetical protein [Pyrococcus abyssi]
Length = 121
Score = 112 bits (281), Expect = 1e-24
Identities = 58/110 (52%), Positives = 76/110 (68%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+VVR DLK+ KGK+A Q +H AV+A + + E ++W + GQ KVVVK + L
Sbjct: 11 IVVRKDLKLSKGKLAVQVAHGAVTAAFKAYKEKREWFEKWFHEGQKKVVVKVESLDELFK 70
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
L A A+ L L +LIQDAG T+I PG+ TVL IGPGP+++IDKVTGHLKL
Sbjct: 71 LKAEAEKLNLPTALIQDAGLTEIPPGTITVLAIGPGPSEIIDKVTGHLKL 120
>gi|14591321|ref|NP_143399.1| hypothetical protein [Pyrococcus horikoshii]
gi|6686200|sp|O74017|YF39_PYRHO HYPOTHETICAL PROTEIN PH1539
gi|7519187|pir||A71031 hypothetical protein PH1539 - Pyrococcus horikoshii
gi|3257966|dbj|BAA30649.1| (AP000006) 121aa long hypothetical protein [Pyrococcus horikoshii]
Length = 121
Score = 109 bits (273), Expect = 1e-23
Identities = 56/110 (50%), Positives = 75/110 (67%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+V R DLK+ KGK+AAQ +H AV+A + ++ E + W GQ KVVVK EE L
Sbjct: 11 IVARADLKLSKGKLAAQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKVESEEELFK 70
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
L A A+ LGL +LI+DAG T+I PG+ TVL +GP P +++DKVTG+LKL
Sbjct: 71 LKAEAEKLGLPNALIRDAGLTEIPPGTVTVLAVGPAPEEIVDKVTGNLKL 120
>gi|13813307|gb|AAK40521.1| (AE006655) Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 120
Score = 107 bits (268), Expect = 4e-23
Identities = 54/114 (47%), Positives = 76/114 (66%), Gaps = 4/114 (3%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRN----PEMLKQWEYCGQPKVVVKAPDEE 301
+VVR D+KMGKGK+AAQ +HAAV+ I N E L +W + GQPK++VK +
Sbjct: 6 IVVRSDIKMGKGKIAAQVAHAAVTLVVSIINSNNLRWKEWLNEWLHQGQPKIIVKVNSLD 65
Query: 300 TLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+I+ A+ + L S+I+DAG+TQ+ PG+ T LGIGP P +L+D +TG LKL
Sbjct: 66 EIISRAKKAETMNLPFSIIEDAGKTQLEPGTITCLGIGPAPENLVDSITGDLKL 119
>gi|2495766|sp|Q60363|Y051_METJA HYPOTHETICAL PROTEIN MJ0051
gi|2129070|pir||C64306 hypothetical protein YBL057c homolog - Methanococcus jannaschii
gi|1590848|gb|AAB98032.1| (U67463) conserved hypothetical protein [Methanococcus jannaschii]
Length = 115
Score = 105 bits (263), Expect = 2e-22
Identities = 53/110 (48%), Positives = 72/110 (65%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+V+R DL MGKGK+ AQ HA + A+ +R+NP + +W GQ KVVVK E+ LI
Sbjct: 5 VVIRNDLGMGKGKMVAQGGHAIIEAFLDAKRKNPRAVDEWLREGQKKVVVKVNSEKELID 64
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A+ GL S+I+DAG TQ+ PG+ T + IGP + IDK+TGHLKL
Sbjct: 65 IYNKARSEGLPCSIIRDAGHTQLEPGTLTAVAIGPEKDEKIDKITGHLKL 114
>gi|6686188|sp|O27732|YG97_METTH HYPOTHETICAL PROTEIN MTH1697
gi|7482163|pir||H69093 conserved hypothetical protein MTH1697 - Methanobacterium
thermoautotrophicum (strain Delta H)
gi|2622828|gb|AAB86169.1| (AE000927) conserved protein [Methanothermobacter
thermautotrophicus]
Length = 112
Score = 95.5 bits (236), Expect = 2e-19
Identities = 48/110 (43%), Positives = 70/110 (63%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
++VR DLKMGKGK+AAQ HA++ ++K R + +++WE G KV+V + L+
Sbjct: 5 IIVRSDLKMGKGKIAAQACHASIGSFK---RTEEDKIRKWELEGSKKVIVSVNSLDELLE 61
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ K G++ L++DAG TQI G+ T LGIGP + IDK+TG LKL
Sbjct: 62 IYRAVKEAGISNYLVRDAGHTQIPAGTITCLGIGPDDDEKIDKITGDLKL 111
>gi|8248747|emb|CAB62849.2| (AL035475) conserved hypothetical protein MAL4P2.08 [Plasmodium
falciparum]
Length = 189
Score = 92.4 bits (228), Expect = 2e-18
Identities = 47/120 (39%), Positives = 73/120 (60%), Gaps = 12/120 (10%)
Frame = -3
Query: 462 VRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQ------------WEYCGQPKVVV 319
VR D+KM KGK+ +QC HA +S Y++I +RN ++ + W+ GQ K+V+
Sbjct: 69 VRTDIKMTKGKICSQCCHACLSVYEKILKRNNKIKDELQQKNSLTYFDVWKKTGQKKIVL 128
Query: 318 KAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
K E + + + A+ L S+I DAGRTQI P ++TV+ I P P ++++K+TG LKL
Sbjct: 129 KISSLEEMFEIESKAQKENLITSIIVDAGRTQIEPNTETVIAIEPVPDEIVNKITGDLKL 188
>gi|10639254|emb|CAC11256.1| (AL445063) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 117
Score = 92.0 bits (227), Expect = 2e-18
Identities = 44/110 (40%), Positives = 69/110 (62%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+ VR DL MGKGK+AAQ +HAAV+ + + N ++ +W GQ K+VVK D + ++
Sbjct: 7 IAVRKDLDMGKGKIAAQVAHAAVTCAIRSMKINRDVFNEWYDEGQRKIVVKVNDLDEIME 66
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A +G+ ++QD G TQ+ PG+ T +G+GP + +DK+TG KL
Sbjct: 67 IKRMADSMGIVNEIVQDRGYTQVEPGTITCIGLGPDEEEKLDKITGKYKL 116
>gi|13541018|ref|NP_110706.1| Uncharacterized conserved protein [Thermoplasma volcanium]
gi|14324402|dbj|BAB59330.1| (AP000991) hypothetical protein [Thermoplasma volcanium]
Length = 117
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/110 (40%), Positives = 66/110 (60%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+ VR DL MGKGK+AAQ +HAAVS + + ++ +W GQ K+VVK P+ + +
Sbjct: 7 VAVRKDLDMGKGKIAAQVAHAAVSCAIKAMKEKKKIFDEWMDEGQKKIVVKVPNVDEIYI 66
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A +G+ +IQD G TQ+ PG+ T +G+GP +D +TG KL
Sbjct: 67 IKKKADSMGIINEVIQDRGYTQVEPGTVTCIGLGPDYEVYLDDITGKYKL 116
>gi|14601543|ref|NP_148083.1| hypothetical protein [Aeropyrum pernix]
gi|6686216|sp|Q9YBD6|YG61_AERPE HYPOTHETICAL PROTEIN APE1661
gi|7516651|pir||A72547 hypothetical protein APE1661 - Aeropyrum pernix (strain K1)
gi|5105349|dbj|BAA80662.1| (AP000062) 124aa long hypothetical protein [Aeropyrum pernix]
Length = 124
Score = 88.2 bits (217), Expect = 4e-17
Identities = 47/115 (40%), Positives = 70/115 (60%), Gaps = 4/115 (3%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSA-YKQIQRRNPEM---LKQWEYCGQPKVVVKAPDEE 301
+VVR DL MG+GK AAQ +HA+ A + ++ PE L+ W GQ KVV++
Sbjct: 10 IVVRRDLGMGRGKAAAQAAHASCEAVFLILESGRPEWRRWLEMWRLQGQAKVVLRVESLA 69
Query: 300 TLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY 136
L + + A GL S ++DAG+TQ+ PG+ T +GP P+ L+D++TG LKL+
Sbjct: 70 ELQEVYSKAVEEGLPASFVRDAGKTQLEPGTPTAAAVGPAPSRLVDRITGGLKLF 124
>gi|11499678|ref|NP_070920.1| conserved hypothetical protein [Archaeoglobus fulgidus]
gi|6686223|sp|O28185|YK95_ARCFU HYPOTHETICAL PROTEIN AF2095
gi|7483205|pir||G69511 conserved hypothetical protein AF2095 - Archaeoglobus fulgidus
gi|2648437|gb|AAB89160.1| (AE000959) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 115
Score = 87.0 bits (214), Expect = 8e-17
Identities = 47/110 (42%), Positives = 68/110 (61%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIA 289
+VVR DLK+ +GK+A Q +HAA+ Y + + + ++W GQ KVV+K E L+
Sbjct: 7 IVVRDDLKLSRGKLAVQVAHAAIIGYL---KSDSSLRRKWLDEGQKKVVLKVKSLEELLG 63
Query: 288 LLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ A+ LGL L+QDAG T++ PG+ T + IGP IDKVTG+L L
Sbjct: 64 IKHKAESLGLVTGLVQDAGLTEVPPGTITAVVIGPDEERKIDKVTGNLPL 113
>gi|6686094|sp|O76387|Y248_CAEEL HYPOTHETICAL 33.7 KDA PROTEIN C24G6.8 IN CHROMOSOME V
gi|7496416|pir||T33180 hypothetical protein C24G6.8 - Caenorhabditis elegans
gi|3193185|gb|AAC19215.1| (AF067936) Hypothetical protein C24G6.8 [Caenorhabditis elegans]
Length = 316
Score = 83.2 bits (204), Expect = 1e-15
Identities = 51/112 (45%), Positives = 61/112 (53%), Gaps = 2/112 (1%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQR--RNPEMLKQWEYCGQPKVVVKAPDEETL 295
LV LKMG GK+AAQ HA + Y+Q + W GQ K+VVK E L
Sbjct: 205 LVANMSLKMGTGKIAAQVGHATLGVYRQAMNSENGQNAIAAWTRHGQVKIVVKGQSTEQL 264
Query: 294 IALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 139
+ L AK G L+QDAG TQI GS+TVLGI G + +D VTG LKL
Sbjct: 265 MDLCKVAKDAGCYYYLVQDAGYTQIPAGSRTVLGIF-GTVEQVDSVTGGLKL 315
>gi|9634699|ref|NP_038992.1| ORF FPV029 Conserved hypothetical protein [Fowlpox virus]
gi|7271527|gb|AAF44373.1|AF198100_20 (AF198100) ORF FPV029 Conserved hypothetical protein [Fowlpox
virus]
Length = 124
Score = 76.3 bits (186), Expect = 1e-13
Identities = 39/108 (36%), Positives = 65/108 (60%)
Frame = -3
Query: 465 VVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIAL 286
V+R DLKM KG++ +QC H A+SAY++ ++ +P+ LK+W GQ K VK +E ++ +
Sbjct: 19 VIRDDLKMTKGEIVSQCCHGAISAYEKSKKYSPDYLKRWLKNGQVKETVKVDNENEMMDI 78
Query: 285 LAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLK 142
+A +G+ ++Q+ R + TVL IGP P + + +T LK
Sbjct: 79 RENATAIGVNYYIVQNDKRQK----CNTVLVIGPAPNYMFESLTRSLK 122
>gi|7486213|pir||T05298 hypothetical protein F26P21.20 - Arabidopsis thaliana
gi|3688171|emb|CAA21199.1| (AL031804) putative protein [Arabidopsis thaliana]
gi|7270237|emb|CAB80007.1| (AL161582) putative protein [Arabidopsis thaliana]
Length = 210
Score = 59.7 bits (143), Expect = 1e-08
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVV 319
LVVR DLKM GK+A+QC+HAA Y ++ + + +L++WE GQPK+VV
Sbjct: 83 LVVRQDLKMRTGKIASQCAHAATGMYAELMQSDRYLLRRWEENGQPKIVV 132
>gi|7479353|pir||T34684 hypothetical protein SC1B5.06c - Streptomyces coelicolor
gi|3130010|emb|CAA18980.1| (AL023517) hypothetical protein [Streptomyces coelicolor A3(2)]
Length = 249
Score = 37.4 bits (85), Expect = 0.071
Identities = 31/93 (33%), Positives = 40/93 (42%), Gaps = 3/93 (3%)
Frame = -3
Query: 453 DLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHA 274
DL M GK AQ H A A+ ++ W G P V A A
Sbjct: 163 DLDMSAGKAMAQAGHGAQLAWWELSDAERTA---WRDAGFPLSVRTADP----------A 209
Query: 273 KMLGLTVS---LIQDAGRTQIAPGSQTVLGIGP 184
+ GLT +++DAG T+IAPGS TV+ P
Sbjct: 210 RWTGLTTGGLPVVRDAGFTEIAPGSCTVVADHP 242
>gi|11349250|pir||F83446 hypothetical protein PA1593 [imported] - Pseudomonas aeruginosa
(strain PAO1)
gi|9947557|gb|AAG04982.1|AE004587_6 (AE004587) hypothetical protein [Pseudomonas aeruginosa]
Length = 157
Score = 33.5 bits (75), Expect = 1.0
Identities = 24/90 (26%), Positives = 38/90 (41%), Gaps = 7/90 (7%)
Frame = -3
Query: 294 IALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGI-------GPGPADLIDKVTGHLKLY 136
++ L H ++LGLTV + G T P SQ ++G G L+D G
Sbjct: 14 LSALRHCQVLGLTVEAADEKGLTLRLPYSQAIIGNPESGVVHGGAITTLMDTTCG----- 68
Query: 135 *VDFDMTTTPPSQVFEACQILTTKAEFLHP 46
++T FE C L + +++HP
Sbjct: 69 -----ISTVCVLPDFEICPTLDLRIDYMHP 93
>gi|2497556|sp|Q25410|MIPR_LYMST PUTATIVE MOLLUSCAN INSULIN-RELATED PEPTIDE(S) RECEPTOR PRECURSOR
gi|11359823|pir||T43212 insulin-like growth factor 1 receptor precursor - great pond snail
gi|1020140|emb|CAA59353.1| (X84994) putative receptor for molluscan insulin-related peptide(s)
[Lymnaea stagnalis]
Length = 1607
Score = 33.1 bits (74), Expect = 1.3
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = -2
Query: 277 CKNAGTDCKFNSRCWTYSDCTRLSNC 200
C N+ D + RCWTYSDC + NC
Sbjct: 209 CPNSCKDECQSKRCWTYSDCQKGLNC 234
>gi|6754362|ref|NP_035962.1| insulin receptor-related receptor [Mus musculus]
gi|4903002|dbj|BAA77835.1| (AB007135) insulin receptor-related receptor [Mus musculus]
Length = 1300
Score = 32.7 bits (73), Expect = 1.7
Identities = 13/35 (37%), Positives = 18/35 (51%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWARTS 176
PC + + RCWT S C ++ CPR A T+
Sbjct: 190 PCSRTTFSGRTDYRCWTSSHCQKVCPCPRGMACTA 224
>gi|7293999|gb|AAF49356.1| (AE003524) CG13727 gene product [Drosophila melanogaster]
Length = 302
Score = 32.7 bits (73), Expect = 1.7
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = -3
Query: 339 GQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGP 178
G P++ KA ++ + LA A +LG+ +L+ + Q+AP +G+G GP
Sbjct: 219 GSPEISPKALLAKSFLIPLASATVLGIAAALVSNPLLLQLAPVPGIGVGVGVGP 272
>gi|12644000|sp|P14616|IRR_HUMAN INSULIN RECEPTOR-RELATED PROTEIN PRECURSOR (IRR) (IR-RELATED
RECEPTOR)
Length = 1297
Score = 32.3 bits (72), Expect = 2.3
Identities = 14/36 (38%), Positives = 17/36 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWARTSR 173
PC + RCWT S C R+ CP A T+R
Sbjct: 190 PCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTAR 225
>gi|106736|pir||B36502 insulin receptor-related receptor - human (fragment)
Length = 1268
Score = 32.3 bits (72), Expect = 2.3
Identities = 14/36 (38%), Positives = 17/36 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWARTSR 173
PC + RCWT S C R+ CP A T+R
Sbjct: 161 PCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTAR 196
>gi|186555|gb|AAC31759.1| (J05046) insulin receptor-related receptor [Homo sapiens]
Length = 1268
Score = 32.3 bits (72), Expect = 2.3
Identities = 14/36 (38%), Positives = 17/36 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWARTSR 173
PC + RCWT S C R+ CP A T+R
Sbjct: 161 PCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTAR 196
>gi|1019792|emb|CAA91187.1| (Z54364) vicilin [Matteuccia struthiopteris]
Length = 504
Score = 32.0 bits (71), Expect = 3.0
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Frame = -3
Query: 372 NPEMLKQWEYCG--QPKVVVKAPDEETLIALL-AHAKMLGLTVS------LIQDAGRTQI 220
N +M + G +PK ++ DE+ L + AHA +G +S +I +GR +
Sbjct: 238 NDQMFHSFFVAGGQKPKTILSGFDEDVLATVFKAHADEVGDMLSSQTQGPIIYFSGRNES 297
Query: 219 APGSQTVLGIGPGPADLIDKVTG 151
G LG+G D++D+ G
Sbjct: 298 KRGDAAGLGLGKSLTDMLDRYIG 320
>gi|12516819|gb|AAG57556.1|AE005474_4 (AE005474) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
gi|13362779|dbj|BAB36732.1| (AP002561) hypothetical protein [Escherichia coli O157:H7]
Length = 168
Score = 31.2 bits (69), Expect = 5.1
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
Frame = -3
Query: 468 LVVRXDLKMGKGKVAAQCSHAAVSAYKQIQRRN---PEMLKQWEYCG---QPKVVVKAPD 307
LVV DL + + A C+ AA+ + I R+ P+ QW G QPK VK PD
Sbjct: 46 LVVEGDLAACRAALDAGCA-AAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD 104
Query: 306 EETLIALLAHAKMLGLTVSLIQDAGRTQIA 217
++A A ++L L S+ Q ++A
Sbjct: 105 APVIVAESAD-ELLALLTSVRQGVTAGEVA 133
>gi|2497553|sp||IRR_RAT_1 [Segment 1 of 2] INSULIN RECEPTOR-RELATED PROTEIN PRECURSOR (IRR)
(IR-RELATED RECEPTOR)
gi|554462|gb|AAB59692.1| (M90661) insulin receptor-related receptor-alpha subunit [Rattus
norvegicus]
Length = 481
Score = 30.8 bits (68), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + RCWT S C R+ CPR A T
Sbjct: 190 PCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACT 223
>gi|11559992|ref|NP_071548.1| insulin receptor-related receptor [Rattus norvegicus]
gi|425791|dbj|BAA03069.1| (D13966) sIRR-2 [Rattus norvegicus]
Length = 469
Score = 30.8 bits (68), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + RCWT S C R+ CPR A T
Sbjct: 190 PCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACT 223
>gi|2117842|pir||B47417 insulin receptor-related receptor, secreted splice form 2 precursor
- rat
Length = 540
Score = 30.8 bits (68), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + RCWT S C R+ CPR A T
Sbjct: 190 PCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACT 223
>gi|425789|dbj|BAA03068.1| (D13965) sIRR-1 [Rattus norvegicus]
Length = 410
Score = 30.8 bits (68), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (46%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + RCWT S C R+ CPR A T
Sbjct: 190 PCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACT 223
>gi|13517025|dbj|BAB40395.1| (AB047172) DNA gyrase B subunit [marine CFB-group bacterium
MBIC4458]
Length = 474
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = -3
Query: 438 KGKVAAQCSHAAVSAYKQIQRRNP 367
K K+AAQ HAA A + +QR+NP
Sbjct: 276 KVKLAAQARHAAAKAREMVQRKNP 299
>gi|13517031|dbj|BAB40398.1| (AB047175) DNA gyrase B subunit [marine CFB-group bacterium
MBIC4467]
gi|13517041|dbj|BAB40403.1| (AB047180) DNA gyrase B subunit [marine CFB-group bacterium
MBIC4472]
Length = 474
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = -3
Query: 438 KGKVAAQCSHAAVSAYKQIQRRNP 367
K K+AAQ HAA A + +QR+NP
Sbjct: 276 KVKLAAQARHAAAKAREMVQRKNP 299
>gi|124908|sp|P14617|IRR_CAVPO INSULIN RECEPTOR-RELATED PROTEIN PRECURSOR (IRR) (IR-RELATED
RECEPTOR)
gi|387060|gb|AAA37044.1| (J05047) insulin receptor-related receptor precursor [Cavia
porcellus]
Length = 1300
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/34 (38%), Positives = 17/34 (49%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + + RCWT S C R+ CP+ A T
Sbjct: 190 PCARTTFNGHTDYRCWTSSHCQRVCPCPQGLACT 223
>gi|112516|pir||A36502 insulin receptor-related receptor precursor - guinea pig
Length = 1300
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/34 (38%), Positives = 17/34 (49%)
Frame = -2
Query: 280 PCKNAGTDCKFNSRCWTYSDCTRLSNCPRDWART 179
PC + + RCWT S C R+ CP+ A T
Sbjct: 190 PCARTTFNGHTDYRCWTSSHCQRVCPCPQGLACT 223
Database: nr
Posted date: Jul 30, 2001 8:58 PM
Number of letters in database: 230,545,999
Number of sequences in database: 727,771
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 243,483,418
Number of Sequences: 727771
Number of extensions: 4910051
Number of successful extensions: 10736
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 10191
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10711
length of database: 230,545,999
effective HSP length: 112
effective length of database: 149,035,647
effective search space used: 11177673525
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)