Query= gnl|UG|Hs#S1090812 Homo sapiens mRNA for KIAA0692 protein,

partial cds /cds=(0,2353) /gb=AB014592 /gi=3327197 /ug=Hs.100729

/len=4088

         (4088 letters)

 

Database: nr

           576,719 sequences; 181,542,687 total letters

 

Searchingdone

 

                                                                   Score     E

Sequences producing significant alignments:                        (bits)  Value

 

pir||T00354 hypothetical protein KIAA0692 - human (fragment) >gi...  1562  0.0

gb|AAF48735.1| (AE003506) CG8465 gene product [alt 1] [Drosophil...   161  6e-038

gb|AAF48737.1| (AE003506) CG8465 gene product [alt 3] [Drosophil...   161  6e-038

 

>pir||T00354 hypothetical protein KIAA0692 - human (fragment)

            >gi|3327198|dbj|BAA31667.1| (AB014592) KIAA0692 protein

            [Homo sapiens]

            Length = 783

           

 Score = 1562 bits (4000), Expect = 0.0

 Identities = 758/770 (98%), Positives = 758/770 (98%)

 Frame = +3

 

Query: 3    DFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNER 182

            DFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNER

Sbjct: 1    DFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNER 60

 

Query: 183  IYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFXXXXXXXXXXXXVKTAPL 362

            IYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYF            VKTAPL

Sbjct: 61   IYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPL 120

 

Query: 363  FSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRY 542

            FSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRY

Sbjct: 121  FSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRY 180

 

Query: 543  LIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKR 722

            LIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKR

Sbjct: 181  LIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKR 240

 

Query: 723  IRYVVDLYLNTPDKMGYDTPLHFACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICE 902

            IRYVVDLYLNTPDKMGYDTPLHFACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICE

Sbjct: 241  IRYVVDLYLNTPDKMGYDTPLHFACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICE 300

 

Query: 903  RSKNKSVELKERIREYLKGHYYVPLLRAEETSSPVIGELWSPDQTAEASHVSRYGGSPRD 1082

            RSKNKSVELKERIREYLKGHYYVPLLRAEETSSPVIGELWSPDQTAEASHVSRYGGSPRD

Sbjct: 301  RSKNKSVELKERIREYLKGHYYVPLLRAEETSSPVIGELWSPDQTAEASHVSRYGGSPRD 360

 

Query: 1083 PVLTLRAFAGPLSPAKAEDFRKLWKTPPREKAGFLHHVKKSDPERGFERVGRELAHELGY 1262

            PVLTLRAFAGPLSPAKAEDFRKLWKTPPREKAGFLHHVKKSDPERGFERVGRELAHELGY

Sbjct: 361  PVLTLRAFAGPLSPAKAEDFRKLWKTPPREKAGFLHHVKKSDPERGFERVGRELAHELGY 420

 

Query: 1263 PWVEYWEFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQETGEREASCRDKATTSGSNSI 1442

            PWVEYWEFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQETGEREASCRDKATTSGSNSI

Sbjct: 421  PWVEYWEFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQETGEREASCRDKATTSGSNSI 480

 

Query: 1443 SVRAFLDEDDMSLEEIKNRQNAARNNSPPTVGAFGHTRCSAFPLEQEADLIEAAEPGGPH 1622

            SVRAFLDEDDMSLEEIKNRQNAARNNSPPTVGAFGHTRCSAFPLEQEADLIEAAEPGGPH

Sbjct: 481  SVRAFLDEDDMSLEEIKNRQNAARNNSPPTVGAFGHTRCSAFPLEQEADLIEAAEPGGPH 540

 

Query: 1623 SSRNGLCHPLNHSRTLAGKRPKAPHGEEAHLPPVSDLTVEFDKLNLQNIGRSVSKTPDES 1802

            SSRNGLCHPLNHSRTLAGKRPKAPHGEEAHLPPVSDLTVEFDKLNLQNIGRSVSKTPDES

Sbjct: 541  SSRNGLCHPLNHSRTLAGKRPKAPHGEEAHLPPVSDLTVEFDKLNLQNIGRSVSKTPDES 600

 

Query: 1803 TKTKDQILTSRINAVERDLLEPSPADQLGNGHRRTESEMSARIAKMSLSPSSPRHEDQLE 1982

            TKTKDQILTSRINAVERDLLEPSPADQLGNGHRRTESEMSARIAKMSLSPSSPRHEDQLE

Sbjct: 601  TKTKDQILTSRINAVERDLLEPSPADQLGNGHRRTESEMSARIAKMSLSPSSPRHEDQLE 660

 

Query: 1983 VTREPARRLFLFGEEPSKLDQDVLAALECADVDPHQFPAVHRWKSAVLCYSPSDRQSWPS 2162

            VTREPARRLFLFGEEPSKLDQDVLAALECADVDPHQFPAVHRWKSAVLCYSPSDRQSWPS

Sbjct: 661  VTREPARRLFLFGEEPSKLDQDVLAALECADVDPHQFPAVHRWKSAVLCYSPSDRQSWPS 720

 

Query: 2163 PAVKGRFKSQLPDLSGPHSYSPGRNSVAGSNPAKPGLGSPGRYSPVHGSQ 2312

            PAVKGRFKSQLPDLSGPHSYSPGRNSVAGSNPAKPGLGSPGRYSPVHGSQ

Sbjct: 721  PAVKGRFKSQLPDLSGPHSYSPGRNSVAGSNPAKPGLGSPGRYSPVHGSQ 770

 

 

>gb|AAF48735.1| (AE003506) CG8465 gene product [alt 1] [Drosophila melanogaster]

            >gi|7293358|gb|AAF48736.1| (AE003506) CG8465 gene product

            [alt 2] [Drosophila melanogaster]

            Length = 1169

           

 Score =  161 bits (403), Expect = 6e-038

 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%)

 Frame = +3

 

Query: 438  YKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK 617

            ++ P  Q+L  + RK +E G  D    +IW NPR+LI SGD PT ++EGCRYN MH+ A+

Sbjct: 228  FRAPTKQELV-EFRKQIEGGHIDRVKRIIWENPRFLISSGDTPTSLKEGCRYNAMHICAQ 286

 

Query: 618  ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRY-VVDLYLNTPDKMGYDTPLHFA 794

             N+A I QL L  + + +F +L         +   +   ++D YLN PDK   +TPLHFA

Sbjct: 287  VNKARIAQLLLKTISDREFTQLYVGKKGSGKMCAALNISLLDYYLNMPDKGRGETPLHFA 346

 

Query: 795  CKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICERSKNKSVELKERIREYLKGHYYVP 974

             K G+  +V VL S+    K+ RN   K P+++IC R+ N +    +++   L   ++VP

Sbjct: 347  AKNGHVAMVEVLVSYP-ECKSLRNHEGKEPKEIICLRNANATHVTIKKLELLLYDPHFVP 405

 

Query: 975  LLRAE-ETSSPVIGELWSPDQTAEASH-VSRYGGSPRDPVLTLRAFAGPLSPAKAEDFRK 1148

            +LR++  T  P +G+ +SP       H    Y G   D  L + A AGP+S  KA +F +

Sbjct: 406  VLRSQSNTLPPKVGQPFSPKDPPNLQHKADDYEGLSVD--LAISALAGPMSREKAMNFYR 463

 

Query: 1149 LWKTPPR 1169

             WKTPPR

Sbjct: 464  RWKTPPR 470

 

 

 Score = 63.2 bits (151), Expect = 2e-008

 Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 6/89 (6%)

 Frame = +3

 

Query: 1119 SPAKAEDFRKLWKTPPREKAGFLH------HVKKSDPERGFERVGRELAHELGYPWVEYW 1280

            SP+ A+D + L  +  R     L+      H+K +D E+G E VGR+LA +    W EYW

Sbjct: 577  SPSLADDSQILDMSLSRSLNASLNDSFRERHIKNTDIEKGLEVVGRQLARQEQLEWREYW 636

 

Query: 1281 EFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQET 1385

            +FL  F+D+ + EGL RLE Y  ++   +  + ET

Sbjct: 637  DFLDSFLDIGTTEGLARLEAYFLEKTEQQADKSET 671

 

 

 Score = 56.2 bits (133), Expect = 3e-006

 Identities = 31/77 (40%), Positives = 41/77 (52%)

 Frame = +3

 

Query: 1905 TESEMSARIAKMSLSPSSPRHEDQLEVTREPARRLFLFGEEPSKLDQDVLAALECADVDP 2084

            +E E + R    SLSP        + +  EP   LF+FG EP+K D DVL AL   D+D

Sbjct: 964  SEDEENFRTPPQSLSPG-------ISMDLEPRYELFIFGNEPTKRDLDVLNALSNVDIDK 1016

 

Query: 2085 HQFPAVHRWKSAVLCYS 2135

               P V+ WK+A+  YS

Sbjct: 1017 ETLPHVYAWKTAMESYS 1033

 

 

>gb|AAF48737.1| (AE003506) CG8465 gene product [alt 3] [Drosophila melanogaster]

            Length = 1105

           

 Score =  161 bits (403), Expect = 6e-038

 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%)

 Frame = +3

 

Query: 438  YKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK 617

            ++ P  Q+L  + RK +E G  D    +IW NPR+LI SGD PT ++EGCRYN MH+ A+

Sbjct: 164  FRAPTKQELV-EFRKQIEGGHIDRVKRIIWENPRFLISSGDTPTSLKEGCRYNAMHICAQ 222

 

Query: 618  ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRY-VVDLYLNTPDKMGYDTPLHFA 794

             N+A I QL L  + + +F +L         +   +   ++D YLN PDK   +TPLHFA

Sbjct: 223  VNKARIAQLLLKTISDREFTQLYVGKKGSGKMCAALNISLLDYYLNMPDKGRGETPLHFA 282

 

Query: 795  CKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICERSKNKSVELKERIREYLKGHYYVP 974

             K G+  +V VL S+    K+ RN   K P+++IC R+ N +    +++   L   ++VP

Sbjct: 283  AKNGHVAMVEVLVSYP-ECKSLRNHEGKEPKEIICLRNANATHVTIKKLELLLYDPHFVP 341

 

Query: 975  LLRAE-ETSSPVIGELWSPDQTAEASH-VSRYGGSPRDPVLTLRAFAGPLSPAKAEDFRK 1148

            +LR++  T  P +G+ +SP       H    Y G   D  L + A AGP+S  KA +F +

Sbjct: 342  VLRSQSNTLPPKVGQPFSPKDPPNLQHKADDYEGLSVD--LAISALAGPMSREKAMNFYR 399

 

Query: 1149 LWKTPPR 1169

             WKTPPR

Sbjct: 400  RWKTPPR 406

 

 

 Score = 63.2 bits (151), Expect = 2e-008

 Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 6/89 (6%)

 Frame = +3

 

Query: 1119 SPAKAEDFRKLWKTPPREKAGFLH------HVKKSDPERGFERVGRELAHELGYPWVEYW 1280

            SP+ A+D + L  +  R     L+      H+K +D E+G E VGR+LA +    W EYW

Sbjct: 513  SPSLADDSQILDMSLSRSLNASLNDSFRERHIKNTDIEKGLEVVGRQLARQEQLEWREYW 572

 

Query: 1281 EFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQET 1385

            +FL  F+D+ + EGL RLE Y  ++   +  + ET

Sbjct: 573  DFLDSFLDIGTTEGLARLEAYFLEKTEQQADKSET 607

 

 

 Score = 56.2 bits (133), Expect = 3e-006

 Identities = 31/77 (40%), Positives = 41/77 (52%)

 Frame = +3

 

Query: 1905 TESEMSARIAKMSLSPSSPRHEDQLEVTREPARRLFLFGEEPSKLDQDVLAALECADVDP 2084

            +E E + R    SLSP        + +  EP   LF+FG EP+K D DVL AL   D+D

Sbjct: 900  SEDEENFRTPPQSLSPG-------ISMDLEPRYELFIFGNEPTKRDLDVLNALSNVDIDK 952

 

Query: 2085 HQFPAVHRWKSAVLCYS 2135

               P V+ WK+A+  YS

Sbjct: 953  ETLPHVYAWKTAMESYS 969

 

 

  Database: nr

    Posted date:  Oct 24, 2000  1:47 AM

  Number of letters in database: 181,542,687

  Number of sequences in database:  576,719

 

Lambda     K      H

   0.318    0.135    0.000

 

Gapped

Lambda     K      H

   0.270   0.0470    0.000

 

 

Matrix: BLOSUM62

Gap Penalties: Existence: 11, Extension: 1

Number of Hits to DB: 1504828474

Number of Sequences: 576719

Number of extensions: 36979442

Number of successful extensions: 123565

Number of sequences better than 1.0e-04: 6

Number of HSP's better than  0.0 without gapping: 3

Number of HSP's successfully gapped in prelim test: 0

Number of HSP's that attempted gapping in prelim test: 123547

Number of HSP's gapped (non-prelim): 12

length of query: 1362

length of database: 181,542,687

effective HSP length: 57

effective length of query: 1305

effective length of database: 148,669,704

effective search space: 194013963720

effective search space used: 194013963720

frameshift window, decay const: 50,  0.1

T: 12

A: 40

X1: 16 ( 7.3 bits)

X2: 38 (14.8 bits)

X3: 64 (24.9 bits)

S1: 41 (21.7 bits)

S2: 120 (51.2 bits)